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Statements

Subject Item
n2:RIV%2F68081707%3A_____%2F10%3A00342607%21RIV11-MSM-68081707
rdf:type
n16:Vysledek skos:Concept
dcterms:description
In this paper we used voltammetry at the mercury-based electrodes for the monitoring of DNA modification with cisdiamminedichloroplatinum (cisplatin), a representative of metallodrugs used in the treatment of various types of cancer or being developed for such purpose. Application of the electrochemical technique in studies of DNA reactivity with various anticancer platinum compounds, as well as for an easy determination of the extent of DNA platination in studies of its biochemical effects, is discussed. In this paper we used voltammetry at the mercury-based electrodes for the monitoring of DNA modification with cisdiamminedichloroplatinum (cisplatin), a representative of metallodrugs used in the treatment of various types of cancer or being developed for such purpose. Application of the electrochemical technique in studies of DNA reactivity with various anticancer platinum compounds, as well as for an easy determination of the extent of DNA platination in studies of its biochemical effects, is discussed.
dcterms:title
Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes
skos:prefLabel
Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes
skos:notation
RIV/68081707:_____/10:00342607!RIV11-MSM-68081707
n5:aktivita
n13:P n13:Z
n5:aktivity
P(1QS500040581), P(GP204/07/P476), P(IAA500040701), P(LC06035), Z(AV0Z50040507), Z(AV0Z50040702)
n5:cisloPeriodika
7
n5:dodaniDat
n18:2011
n5:domaciTvurceVysledku
n8:1260944 n8:7506481 n8:3288641 n8:4171373 n8:9637540 n8:6875181
n5:druhVysledku
n9:J
n5:duvernostUdaju
n7:S
n5:entitaPredkladatele
n15:predkladatel
n5:idSjednocenehoVysledku
253822
n5:idVysledku
RIV/68081707:_____/10:00342607
n5:jazykVysledku
n17:eng
n5:klicovaSlova
cisplatin; electrochemical analysis of DNA; mercury electrode
n5:klicoveSlovo
n12:mercury%20electrode n12:electrochemical%20analysis%20of%20DNA n12:cisplatin
n5:kodStatuVydavatele
US - Spojené státy americké
n5:kontrolniKodProRIV
[1EC739F84199]
n5:nazevZdroje
Analytical Chemistry
n5:obor
n11:BO
n5:pocetDomacichTvurcuVysledku
6
n5:pocetTvurcuVysledku
6
n5:projekt
n14:IAA500040701 n14:GP204%2F07%2FP476 n14:LC06035 n14:1QS500040581
n5:rokUplatneniVysledku
n18:2010
n5:svazekPeriodika
82
n5:tvurceVysledku
Horáková, Petra Havran, Luděk Pivoňková, Hana Vidláková, Pavlína Fojta, Miroslav Těsnohlídková, Lucie
n5:wos
000276004000051
n5:zamer
n6:AV0Z50040702 n6:AV0Z50040507
s:issn
0003-2700
s:numberOfPages
8