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Statements

Subject Item
n2:RIV%2F68081707%3A_____%2F02%3A17023143%21RIV%2F2003%2FGA0%2FA17003%2FN
rdf:type
skos:Concept n10:Vysledek
dcterms:description
The paper describes molecular mechanisms underlying antitumor activity of the novel PhaseII antitumor platinum drug BBR3464. The results indicate that the crucial role in these mechanisms is played by interstrand cross-links formed by this drug in DNA. The paper describes molecular mechanisms underlying antitumor activity of the novel PhaseII antitumor platinum drug BBR3464. The results indicate that the crucial role in these mechanisms is played by interstrand cross-links formed by this drug in DNA.
dcterms:title
DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair.
skos:prefLabel
DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair.
skos:notation
RIV/68081707:_____/02:17023143!RIV/2003/GA0/A17003/N
n3:strany
48076;48086
n3:aktivita
n9:Z n9:P
n3:aktivity
P(GA305/02/1552), P(IAA5004101), P(NL6058), Z(AV0Z5004920)
n3:cisloPeriodika
50
n3:dodaniDat
n4:2003
n3:domaciTvurceVysledku
n14:4571932 n14:7988346 n14:1564552
n3:druhVysledku
n15:J
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
643498
n3:idVysledku
RIV/68081707:_____/02:17023143
n3:jazykVysledku
n18:eng
n3:klicovaSlova
DNA; platinum; cancer
n3:klicoveSlovo
n5:platinum n5:DNA n5:cancer
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[75BE0ACD07D7]
n3:nazevZdroje
Journal of Biological Chemistry
n3:obor
n16:BO
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
4
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n11:GA305%2F02%2F1552 n11:NL6058 n11:IAA5004101
n3:rokUplatneniVysledku
n4:2002
n3:svazekPeriodika
277
n3:tvurceVysledku
Kašpárková, Jana Zehnulová, Jana Brabec, Viktor Farrell, N.
n3:zamer
n13:AV0Z5004920
s:issn
0021-9258
s:numberOfPages
11