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Statements

Subject Item
n2:RIV%2F68081707%3A_____%2F01%3A17013004%21RIV%2F2003%2FAV0%2FA17003%2FN
rdf:type
n8:Vysledek skos:Concept
dcterms:description
The effect of the single, site-specific interstrand cross-link formed by cisplatin or transplatin on the thermal stability and energetics of 20-base pairs DNA duplex was reported. The results indicate that the impact of interstrand cross-links of cisplatin and transplatin on DNA is different which might be also associated with distinctly different antitumor effects of these platinum compounds. The effect of the single, site-specific interstrand cross-link formed by cisplatin or transplatin on the thermal stability and energetics of 20-base pairs DNA duplex was reported. The results indicate that the impact of interstrand cross-links of cisplatin and transplatin on DNA is different which might be also associated with distinctly different antitumor effects of these platinum compounds.
dcterms:title
Thermal and Thermodynamic Properties of Duplex DNA Containing Site-specific Interstrand Cross-link of Antitumor Cisplatin or Its Clinically Ineffective Trans Isomer. Thermal and Thermodynamic Properties of Duplex DNA Containing Site-specific Interstrand Cross-link of Antitumor Cisplatin or Its Clinically Ineffective Trans Isomer.
skos:prefLabel
Thermal and Thermodynamic Properties of Duplex DNA Containing Site-specific Interstrand Cross-link of Antitumor Cisplatin or Its Clinically Ineffective Trans Isomer. Thermal and Thermodynamic Properties of Duplex DNA Containing Site-specific Interstrand Cross-link of Antitumor Cisplatin or Its Clinically Ineffective Trans Isomer.
skos:notation
RIV/68081707:_____/01:17013004!RIV/2003/AV0/A17003/N
n3:strany
9655;9661
n3:aktivita
n10:Z n10:P
n3:aktivity
P(GA301/00/0556), P(GA305/99/0695), P(IAA5004702), P(NL6058), P(NL6069), Z(AV0Z5004920)
n3:cisloPeriodika
13
n3:dodaniDat
n11:2003
n3:domaciTvurceVysledku
n17:9914048 n17:7988346
n3:druhVysledku
n12:J
n3:duvernostUdaju
n6:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
698713
n3:idVysledku
RIV/68081707:_____/01:17013004
n3:jazykVysledku
n14:eng
n3:klicovaSlova
N/A
n3:klicoveSlovo
n15:N%2FA
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[8778060FD399]
n3:nazevZdroje
Journal of Biological Chemistry
n3:obor
n13:BO
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
2
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n4:GA301%2F00%2F0556 n4:NL6069 n4:NL6058 n4:GA305%2F99%2F0695 n4:IAA5004702
n3:rokUplatneniVysledku
n11:2001
n3:svazekPeriodika
276
n3:tvurceVysledku
Hofr, Ctirad Brabec, Viktor
n3:zamer
n16:AV0Z5004920
s:issn
0021-9258
s:numberOfPages
7