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Statements

Subject Item
n2:RIV%2F67985904%3A_____%2F14%3A00428035%21RIV15-GA0-67985904
rdf:type
n13:Vysledek skos:Concept
dcterms:description
Genes that are expressed in skeletal muscles may play a role in prenatal muscle development and postnatal muscle growth and can be considered candidates for economically important traits. Four porcine genes that were differentially expressed in skeletal muscles of Czech Large White and Wild Boar (SORT1, EMP3, IL18, and BTG2) were selected to search for polymorphism, linkage assignment, and association analysis with carcass traits. Through comparative sequencing of portions of the genes numerous polymorphisms were revealed (SORT1-21, EMP3-6, IL18-41, BTG2-9). Linkage analysis in a Meishan Pietrain F2 pedigree showed the positions of the genes relative to other genes and markers on the respective chromosomes - SORT1 on SSC4, EMP3 on SSC6, IL18 and BTG2 on SSC9. Preliminary association analysis in pig commercial crosses with selected SNPs showed associations with several carcass traits at nominal P value of < 0.05, which may indicate their involvement in muscle growth and fat deposition. The tested polymorphisms may not be causal for the associations, but they may be in linkage disequilibrium with causative mutations. Genes that are expressed in skeletal muscles may play a role in prenatal muscle development and postnatal muscle growth and can be considered candidates for economically important traits. Four porcine genes that were differentially expressed in skeletal muscles of Czech Large White and Wild Boar (SORT1, EMP3, IL18, and BTG2) were selected to search for polymorphism, linkage assignment, and association analysis with carcass traits. Through comparative sequencing of portions of the genes numerous polymorphisms were revealed (SORT1-21, EMP3-6, IL18-41, BTG2-9). Linkage analysis in a Meishan Pietrain F2 pedigree showed the positions of the genes relative to other genes and markers on the respective chromosomes - SORT1 on SSC4, EMP3 on SSC6, IL18 and BTG2 on SSC9. Preliminary association analysis in pig commercial crosses with selected SNPs showed associations with several carcass traits at nominal P value of < 0.05, which may indicate their involvement in muscle growth and fat deposition. The tested polymorphisms may not be causal for the associations, but they may be in linkage disequilibrium with causative mutations.
dcterms:title
Polymorphism, linkage mapping, and association analysis with carcass traits of four porcine candidate genes selected from gene-expression profiles of Czech Large White and Wild Boar muscles Polymorphism, linkage mapping, and association analysis with carcass traits of four porcine candidate genes selected from gene-expression profiles of Czech Large White and Wild Boar muscles
skos:prefLabel
Polymorphism, linkage mapping, and association analysis with carcass traits of four porcine candidate genes selected from gene-expression profiles of Czech Large White and Wild Boar muscles Polymorphism, linkage mapping, and association analysis with carcass traits of four porcine candidate genes selected from gene-expression profiles of Czech Large White and Wild Boar muscles
skos:notation
RIV/67985904:_____/14:00428035!RIV15-GA0-67985904
n3:aktivita
n10:I n10:S n10:P
n3:aktivity
I, P(ED1.1.00/02.0068), P(GA523/09/0844), S
n3:cisloPeriodika
3
n3:dodaniDat
n9:2015
n3:domaciTvurceVysledku
n5:9635343 n5:8271275 n5:4050584 n5:3748030
n3:druhVysledku
n14:J
n3:duvernostUdaju
n6:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
37435
n3:idVysledku
RIV/67985904:_____/14:00428035
n3:jazykVysledku
n15:eng
n3:klicovaSlova
pig; single nucleotide polymorphism; DNA markers
n3:klicoveSlovo
n16:DNA%20markers n16:single%20nucleotide%20polymorphism n16:pig
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[219529028AA9]
n3:nazevZdroje
Czech Journal of Animal Science
n3:obor
n12:GI
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
11
n3:projekt
n8:GA523%2F09%2F0844 n8:ED1.1.00%2F02.0068
n3:rokUplatneniVysledku
n9:2014
n3:svazekPeriodika
59
n3:tvurceVysledku
Šprysl, M. Horák, Pavel Stratil, Antonín Dvořáková, Věra Bartenschlager, H. Palánová, Anna Geldermann, H. Čítek, J. Stupka, R. Knoll, A. Chalupová, P.
n3:wos
000335889500003
s:issn
1212-1819
s:numberOfPages
12