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Statements

Subject Item
n2:RIV%2F67985904%3A_____%2F12%3A00377162%21RIV13-AV0-67985904
rdf:type
skos:Concept n14:Vysledek
dcterms:description
The goal of the present study was to develop a porcine spinal cord injury (SCI) model, and to describe the neurological outcome and characterize the corresponding quantitative and qualitative histological changes at 4-9 months after injury. Adult Gottingen-Minnesota minipigs were anesthetized and placed in a spine immobilization frame. The exposed T12 spinal segment was compressed in a dorso-ventral direction using a 5-mm-diameter circular bar with a progressively increasing peak force (1.5, 2.0, or 2.5 kg) at a velocity of 3 cm/sec. During recovery, motor and sensory function were periodically monitored. The goal of the present study was to develop a porcine spinal cord injury (SCI) model, and to describe the neurological outcome and characterize the corresponding quantitative and qualitative histological changes at 4-9 months after injury. Adult Gottingen-Minnesota minipigs were anesthetized and placed in a spine immobilization frame. The exposed T12 spinal segment was compressed in a dorso-ventral direction using a 5-mm-diameter circular bar with a progressively increasing peak force (1.5, 2.0, or 2.5 kg) at a velocity of 3 cm/sec. During recovery, motor and sensory function were periodically monitored.
dcterms:title
Chronic Spinal Compression Model in Minipigs: A Systematic Behavioral, Qualitative, and Quantitative Neuropathological Study Chronic Spinal Compression Model in Minipigs: A Systematic Behavioral, Qualitative, and Quantitative Neuropathological Study
skos:prefLabel
Chronic Spinal Compression Model in Minipigs: A Systematic Behavioral, Qualitative, and Quantitative Neuropathological Study Chronic Spinal Compression Model in Minipigs: A Systematic Behavioral, Qualitative, and Quantitative Neuropathological Study
skos:notation
RIV/67985904:_____/12:00377162!RIV13-AV0-67985904
n14:predkladatel
n15:ico%3A67985904
n3:aktivita
n12:P n12:Z
n3:aktivity
P(1M0538), P(TA01011466), Z(AV0Z50450515)
n3:cisloPeriodika
3
n3:dodaniDat
n20:2013
n3:domaciTvurceVysledku
n11:5434505 n11:4536096 n11:1947788
n3:druhVysledku
n10:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
127143
n3:idVysledku
RIV/67985904:_____/12:00377162
n3:jazykVysledku
n17:eng
n3:klicovaSlova
axonal loss; chronic spinal injury; minipig
n3:klicoveSlovo
n18:axonal%20loss n18:chronic%20spinal%20injury n18:minipig
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[163F2C0BB2EE]
n3:nazevZdroje
Journal of Neurotrauma
n3:obor
n9:FH
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
14
n3:projekt
n16:1M0538 n16:TA01011466
n3:rokUplatneniVysledku
n20:2012
n3:svazekPeriodika
29
n3:tvurceVysledku
Tomori, Z. Motlík, Jan Scadeng, M. Johe, K. Beattie, M. Marsala, S. Lazar, P. Keshavarzi, S. Juhás, Štefan Marsala, M. Schulteis, G. Juhásová, Jana Navarro, R. Ciacci, J. D.
n3:wos
000300621500006
n3:zamer
n4:AV0Z50450515
s:issn
0897-7151
s:numberOfPages
15
n19:doi
10.1089/neu.2011.2076