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Statements

Subject Item
n2:RIV%2F67985904%3A_____%2F11%3A00368158%21RIV12-AV0-67985904
rdf:type
skos:Concept n12:Vysledek
dcterms:description
Pulsed laser deposition was proved as a suitable method for hydroxyapatite (HA) coating of coaxial poly-ε-caprolactone/polyvinylalcohol (PCL/PVA) nanofibers. The fibrous morphology of PCL/PVA nanofibers was preserved, if the nanofiber scaffold was coated with a thin layers of HA (200 nm and 400 nm). Increasing thickness of HA, however, resulted in a gradual loss of fibrous character. In addition, biomechanical properties were improved after HA deposition on PCL/PVA nanofibers as the value of Young's moduli of elasticity significantly increased. Cle arly, thin-layer hydroxyapatite deposition on a nanofiber surface stimulated mesenchymal stem cell viability and their differentiation into osteoblasts. The optimal depth of HA was 800 nm. Pulsed laser deposition was proved as a suitable method for hydroxyapatite (HA) coating of coaxial poly-ε-caprolactone/polyvinylalcohol (PCL/PVA) nanofibers. The fibrous morphology of PCL/PVA nanofibers was preserved, if the nanofiber scaffold was coated with a thin layers of HA (200 nm and 400 nm). Increasing thickness of HA, however, resulted in a gradual loss of fibrous character. In addition, biomechanical properties were improved after HA deposition on PCL/PVA nanofibers as the value of Young's moduli of elasticity significantly increased. Cle arly, thin-layer hydroxyapatite deposition on a nanofiber surface stimulated mesenchymal stem cell viability and their differentiation into osteoblasts. The optimal depth of HA was 800 nm.
dcterms:title
Optimized conditions for mesenchymal stem cells to differentiate into osteoblasts on a collagen/hydroxyapatite matrix Optimized conditions for mesenchymal stem cells to differentiate into osteoblasts on a collagen/hydroxyapatite matrix
skos:prefLabel
Optimized conditions for mesenchymal stem cells to differentiate into osteoblasts on a collagen/hydroxyapatite matrix Optimized conditions for mesenchymal stem cells to differentiate into osteoblasts on a collagen/hydroxyapatite matrix
skos:notation
RIV/67985904:_____/11:00368158!RIV12-AV0-67985904
n12:predkladatel
n13:ico%3A67985904
n3:aktivita
n16:I n16:S n16:P n16:Z
n3:aktivity
I, P(1M0510), P(2B06130), P(7E09088), P(GA202/09/1151), P(GAP304/10/1307), P(GP106/09/P226), P(IAA500390702), S, Z(AV0Z50390512), Z(AV0Z50390703), Z(AV0Z50450515), Z(MSM4977751303)
n3:cisloPeriodika
2
n3:dodaniDat
n9:2012
n3:domaciTvurceVysledku
n15:4536096
n3:druhVysledku
n17:J
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
218785
n3:idVysledku
RIV/67985904:_____/11:00368158
n3:jazykVysledku
n10:eng
n3:klicovaSlova
collagen/HA scaffold; MSCs; osteoblasts
n3:klicoveSlovo
n18:collagen%2FHA%20scaffold n18:osteoblasts n18:MSCs
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[73CC85CEC311]
n3:nazevZdroje
Journal of Biomedical Materials Research. Part A
n3:obor
n4:BO
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
14
n3:projekt
n5:GAP304%2F10%2F1307 n5:1M0510 n5:GP106%2F09%2FP226 n5:7E09088 n5:GA202%2F09%2F1151 n5:IAA500390702 n5:2B06130
n3:rokUplatneniVysledku
n9:2011
n3:svazekPeriodika
99A
n3:tvurceVysledku
Tvrdík, D. Jakubová, Radka Klepáček, J. Tonar, Z. Prosecká, Eva Juhásová, Jana Melčáková, Š. Jančář, J. Plencner, Martin Nečas, A. Rampichová, Michala Kochová, P. Vojtová, L. Amler, Evžen
n3:wos
000295142400018
n3:zamer
n6:AV0Z50390703 n6:AV0Z50450515 n6:AV0Z50390512 n6:MSM4977751303
s:issn
1549-3296
s:numberOfPages
9
n20:doi
10.1002/jbm.a.33189