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Statements

Subject Item
n2:RIV%2F67985904%3A_____%2F10%3A00351847%21RIV11-GA0-67985904
rdf:type
n17:Vysledek skos:Concept
dcterms:description
Hydrogels prepared from a mixture of fibrin and high-molecular weight (MW) hyaluronic acid (HA) were found to be suitable scaffolds for chondrocyte seeding and pig knee cartilage regeneration. Collagen in the hydrogels is not necessary for the formation of biomechanically stable tissue. Regenerated cartilage showed very good biomechanical and histological properties only 6 months after implantation. Notably, the quality of the healing process was dependent on the initial chondrocyte concentration of the scaffolds. These experiments were performed according to good laboratory practice (GLP). Hydrogels prepared from a mixture of fibrin and high-molecular weight (MW) hyaluronic acid (HA) were found to be suitable scaffolds for chondrocyte seeding and pig knee cartilage regeneration. Collagen in the hydrogels is not necessary for the formation of biomechanically stable tissue. Regenerated cartilage showed very good biomechanical and histological properties only 6 months after implantation. Notably, the quality of the healing process was dependent on the initial chondrocyte concentration of the scaffolds. These experiments were performed according to good laboratory practice (GLP).
dcterms:title
Fibrin/Hyaluronic Acid Composite Hydrogels as Appropriate Scaffolds for In Vivo Artificial Cartilage Implantation Fibrin/Hyaluronic Acid Composite Hydrogels as Appropriate Scaffolds for In Vivo Artificial Cartilage Implantation
skos:prefLabel
Fibrin/Hyaluronic Acid Composite Hydrogels as Appropriate Scaffolds for In Vivo Artificial Cartilage Implantation Fibrin/Hyaluronic Acid Composite Hydrogels as Appropriate Scaffolds for In Vivo Artificial Cartilage Implantation
skos:notation
RIV/67985904:_____/10:00351847!RIV11-GA0-67985904
n3:aktivita
n12:S n12:P n12:Z
n3:aktivity
P(GAP304/10/1307), S, Z(AV0Z50390512), Z(AV0Z50390703), Z(AV0Z50450515)
n3:cisloPeriodika
6
n3:dodaniDat
n7:2011
n3:domaciTvurceVysledku
n6:5434505
n3:druhVysledku
n14:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
259043
n3:idVysledku
RIV/67985904:_____/10:00351847
n3:jazykVysledku
n8:eng
n3:klicovaSlova
chondrocyte; composite scaffold; osteochondral defect regeneration
n3:klicoveSlovo
n9:chondrocyte n9:composite%20scaffold n9:osteochondral%20defect%20regeneration
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[E5DD66BA0C12]
n3:nazevZdroje
Asaio Journal
n3:obor
n16:BO
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
11
n3:projekt
n11:GAP304%2F10%2F1307
n3:rokUplatneniVysledku
n7:2010
n3:svazekPeriodika
56
n3:tvurceVysledku
Prosecká, Eva Nečas, A. Koláčná, Lucie Filová, Eva Rampichová, Michala Lytvynets, Andriy Motlík, Jan Varga, F. Uhlík, J. Vajner, L. Amler, Evžen
n3:wos
000283719600014
n3:zamer
n15:AV0Z50390703 n15:AV0Z50450515 n15:AV0Z50390512
s:issn
1058-2916
s:numberOfPages
6