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Statements

Subject Item
n2:RIV%2F67985904%3A_____%2F07%3A00096193%21RIV08-AV0-67985904
rdf:type
n10:Vysledek skos:Concept
dcterms:description
The analysis of expression of pheromone-carrying major urinary proteins (MUPs) from two subspecies of house mice (Mus m. musculus, Mus m. domesticus) was studied. It has been previously shown that commensal populations of the two subspecies can discriminate on the basis of urinary signals. MUPs are predominant urinary proteins that protect pheromones from rapid degradation in a hydrophilic environment, and individuals of M m. musculus tend to rely on these urinary cues in the process of subspecies discrimination more than M m. domesticus individuals. Although it is not precisely known what triggers phenotypic and epigenetic changes of MUP expression, our results show that in the subspecies M m. musculus, sex is a significant factor influencing variations in the regulation of selected MUPs in the liver. Furthermore, male M m. musculus individuals expressed all the studied MUPs' mRNA significantly more than females or individuals of either sex in M m. domesticus. Correspondingly, the pattern of mRNA ... The analysis of expression of pheromone-carrying major urinary proteins (MUPs) from two subspecies of house mice (Mus m. musculus, Mus m. domesticus) was studied. It has been previously shown that commensal populations of the two subspecies can discriminate on the basis of urinary signals. MUPs are predominant urinary proteins that protect pheromones from rapid degradation in a hydrophilic environment, and individuals of M m. musculus tend to rely on these urinary cues in the process of subspecies discrimination more than M m. domesticus individuals. Although it is not precisely known what triggers phenotypic and epigenetic changes of MUP expression, our results show that in the subspecies M m. musculus, sex is a significant factor influencing variations in the regulation of selected MUPs in the liver. Furthermore, male M m. musculus individuals expressed all the studied MUPs' mRNA significantly more than females or individuals of either sex in M m. domesticus. Correspondingly, the pattern of mRNA ... Hlavní močové proteiny (angl. Major Urinary Proteins, MUP) jsou proteinové přenašeče feromónů a byly zjištěny u mnoha druhů savců, především pak u myšovitých hlodavců. Tato práce předkládá důkaz o tom, že u dvou poddruhů myší (Mus musculus and Mus musculus domesticus) vykazují tyto proteiny pohlavní dimorfismus v expresi na úrovni mRNA transkribce a také na úrovni translace. Míra pohlavního dimorfismu je navíc pod-druhově specifická. Je velmi pravděpodobné, že tato proteiny jsou proto důležité pro mezidruhové rozpoznávání.
dcterms:title
Species-specific expression of major urinary proteins in the house mice (Mus musculus and Mus musculus domesticus) Species-specific expression of major urinary proteins in the house mice (Mus musculus and Mus musculus domesticus) Druhově specifická exprese hlavních močových proteinů myší (Mus musculus and Mus musculus domesticus)
skos:prefLabel
Druhově specifická exprese hlavních močových proteinů myší (Mus musculus and Mus musculus domesticus) Species-specific expression of major urinary proteins in the house mice (Mus musculus and Mus musculus domesticus) Species-specific expression of major urinary proteins in the house mice (Mus musculus and Mus musculus domesticus)
skos:notation
RIV/67985904:_____/07:00096193!RIV08-AV0-67985904
n3:strany
861;869
n3:aktivita
n17:Z
n3:aktivity
Z(AV0Z50450515)
n3:cisloPeriodika
4
n3:dodaniDat
n11:2008
n3:domaciTvurceVysledku
n8:7214448
n3:druhVysledku
n16:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
451480
n3:idVysledku
RIV/67985904:_____/07:00096193
n3:jazykVysledku
n14:eng
n3:klicovaSlova
gene expression; MUP; sexual dimorphism
n3:klicoveSlovo
n7:MUP n7:gene%20expression n7:sexual%20dimorphism
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[C76B0A6B454D]
n3:nazevZdroje
Journal of Chemical Ecology
n3:obor
n9:EG
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n11:2007
n3:svazekPeriodika
33
n3:tvurceVysledku
Jedelský, P. Stopka, Pavel Janotová, K. Stopková, R.
n3:zamer
n13:AV0Z50450515
s:issn
0098-0331
s:numberOfPages
9