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Statements

Subject Item
n2:RIV%2F67985904%3A_____%2F04%3A00100592%21RIV%2F2005%2FGA0%2FA21005%2FN
rdf:type
n16:Vysledek skos:Concept
dcterms:description
Subcutaneous application of bovine RNase A conjugated to HYase (bovine hyaluronidase), polyethylene glycol(PEG)and HYase+PEG resulted in a marker reduction of the width of the spermatogenic layers of the mouse testes. The number of sperms in caput epididymidis was significantly desreased in mice injected with conjugated RNase A Subcutaneous application of bovine RNase A conjugated to HYase (bovine hyaluronidase), polyethylene glycol(PEG)and HYase+PEG resulted in a marker reduction of the width of the spermatogenic layers of the mouse testes. The number of sperms in caput epididymidis was significantly desreased in mice injected with conjugated RNase A Subkutánní aplikace bovinní RNase A kojugované s Hyase (bovidní hyaluronidasa,polyethylen glykolem /PEG) snižoval aspermatogenní efekt. Melanomový nádor rostoucí na athymických myších však byl podstatně zmenšen
dcterms:title
Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A Působení ribonukleasy A konjugované hyaluronidasou a PEG na biologické a protinádorové aktivity
skos:prefLabel
Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A Působení ribonukleasy A konjugované hyaluronidasou a PEG na biologické a protinádorové aktivity Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A
skos:notation
RIV/67985904:_____/04:00100592!RIV/2005/GA0/A21005/N
n3:strany
401;410
n3:aktivita
n5:Z n5:P
n3:aktivity
P(GA523/01/0114), Z(AV0Z5045916)
n3:cisloPeriodika
-
n3:dodaniDat
n9:2005
n3:domaciTvurceVysledku
n14:5105153
n3:druhVysledku
n11:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n7:predkladatel
n3:idSjednocenehoVysledku
561922
n3:idVysledku
RIV/67985904:_____/04:00100592
n3:jazykVysledku
n10:eng
n3:klicovaSlova
antitumour;aspermatogenesis;embryotoxicity
n3:klicoveSlovo
n4:aspermatogenesis n4:antitumour n4:embryotoxicity
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[1D6B6135E041]
n3:nazevZdroje
Journal of Controlled Release
n3:obor
n6:EB
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
6
n3:projekt
n15:GA523%2F01%2F0114
n3:rokUplatneniVysledku
n9:2004
n3:svazekPeriodika
94
n3:tvurceVysledku
Poučková, P. Hloušková, D. Škvor, J. Zadinová, M. Matoušek, Josef Souček, J.
n3:zamer
n17:AV0Z5045916
s:issn
0168-3659
s:numberOfPages
10