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Statements

Subject Item
n2:RIV%2F67985904%3A_____%2F02%3A21023127%21RIV%2F2003%2FAV0%2FA21003%2FN
rdf:type
n11:Vysledek skos:Concept
dcterms:description
In this study, butyrolactone I (BL I), a potent and specific inhibitor of cyclin-dependent kinases (cdk), is shown to inhibit germinal vesicle breakdown (GVBD) in pig oocytes. Results suggest that both chromosome condensation and GVBD could occur without activation of cdc2 kinase, whereas an increase in MAP kinase activity may be a requisite for GVBD in pig oocytes in conditions when cdc2 kinase activation is blocked by BL I. In this study, butyrolactone I (BL I), a potent and specific inhibitor of cyclin-dependent kinases (cdk), is shown to inhibit germinal vesicle breakdown (GVBD) in pig oocytes. Results suggest that both chromosome condensation and GVBD could occur without activation of cdc2 kinase, whereas an increase in MAP kinase activity may be a requisite for GVBD in pig oocytes in conditions when cdc2 kinase activation is blocked by BL I.
dcterms:title
Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity. Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity.
skos:prefLabel
Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity. Chromosome Condensation in Pig Oocytes: Lack of a requirement for Either cdc2 Kinase or MAP Kinase Activity.
skos:notation
RIV/67985904:_____/02:21023127!RIV/2003/AV0/A21003/N
n3:strany
110;118
n3:aktivita
n4:Z n4:P
n3:aktivity
P(GA203/99/1459), P(KSK5052113), Z(AV0Z5045916)
n3:cisloPeriodika
N/A
n3:dodaniDat
n16:2003
n3:domaciTvurceVysledku
n7:5434505 n7:2188554 n7:1114921 n7:3887103
n3:druhVysledku
n15:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
640866
n3:idVysledku
RIV/67985904:_____/02:21023127
n3:jazykVysledku
n14:eng
n3:klicovaSlova
GVBD; chromosome condensation; okadaic acid
n3:klicoveSlovo
n12:okadaic%20acid n12:GVBD n12:chromosome%20condensation
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[2E8468976EEB]
n3:nazevZdroje
Molecular Reproduction and Development
n3:obor
n5:EB
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
5
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n13:GA203%2F99%2F1459 n13:KSK5052113
n3:rokUplatneniVysledku
n16:2002
n3:svazekPeriodika
63
n3:tvurceVysledku
Kalous, Jaroslav Kubelka, Michal Motlík, Jan Anger, Martin Schultz, R. M.
n3:zamer
n9:AV0Z5045916
s:issn
1040-452X
s:numberOfPages
9