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Statements

Subject Item
n2:RIV%2F67985904%3A_____%2F02%3A21023119%21RIV%2F2003%2FAV0%2FA21003%2FN
rdf:type
skos:Concept n10:Vysledek
dcterms:description
A thorough characterization of the properties of squamous epithelial cell is necessary in order to improve our understanding of the functional aspects of normal development and malignant aberrations. With our growing awareness of the coding function of glycan chains of cellular glycoconjugates and their interaction with receptors (lectins) in situ, defining the glycophenotype of these cells has become an important issue. Whwreas the commonly applied plant lectins are tools used to map the presence and location of biochemically defined saccharide epitopes, the introduction of endogenous (mammalian) lectins to this analysis enables us to take the step from monitoring the presence of glycan to understanding the functional implications by revealing ligand properties of the detected epitope for issue lectin. A thorough characterization of the properties of squamous epithelial cell is necessary in order to improve our understanding of the functional aspects of normal development and malignant aberrations. With our growing awareness of the coding function of glycan chains of cellular glycoconjugates and their interaction with receptors (lectins) in situ, defining the glycophenotype of these cells has become an important issue. Whwreas the commonly applied plant lectins are tools used to map the presence and location of biochemically defined saccharide epitopes, the introduction of endogenous (mammalian) lectins to this analysis enables us to take the step from monitoring the presence of glycan to understanding the functional implications by revealing ligand properties of the detected epitope for issue lectin.
dcterms:title
Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on bindin Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on bindin
skos:prefLabel
Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on bindin Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on bindin
skos:notation
RIV/67985904:_____/02:21023119!RIV/2003/AV0/A21003/N
n4:strany
845;856
n4:aktivita
n9:Z n9:P
n4:aktivity
P(GA304/02/0463), P(KSK5052113), P(LN00A065), Z(AV0Z5045916)
n4:cisloPeriodika
N/A
n4:dodaniDat
n5:2003
n4:domaciTvurceVysledku
n17:5434505
n4:druhVysledku
n13:J
n4:duvernostUdaju
n12:S
n4:entitaPredkladatele
n15:predkladatel
n4:idSjednocenehoVysledku
642339
n4:idVysledku
RIV/67985904:_____/02:21023119
n4:jazykVysledku
n18:eng
n4:klicovaSlova
epidermis; galectin; glycohistochemistry
n4:klicoveSlovo
n16:glycohistochemistry n16:galectin n16:epidermis
n4:kodStatuVydavatele
DK - Dánské království
n4:kontrolniKodProRIV
[86D2A5375D01]
n4:nazevZdroje
Apmis
n4:obor
n11:EB
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
14
n4:pocetUcastnikuAkce
0
n4:pocetZahranicnichUcastnikuAkce
0
n4:projekt
n8:KSK5052113 n8:GA304%2F02%2F0463 n8:LN00A065
n4:rokUplatneniVysledku
n5:2002
n4:svazekPeriodika
110
n4:tvurceVysledku
Plzák, J. Hercogová, J. Kaltner, H. Betka, J. André, S. Dvořánková, B. Esner, M. Gabius, H. J. Wasano, K. Kodet, R. Smetana jr., K. Holíková, Z. Hrdličková-Celá, E. Motlík, Jan
n4:zamer
n14:AV0Z5045916
s:issn
0903-4641
s:numberOfPages
12