This HTML5 document contains 53 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n7http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F67985823%3A_____%2F14%3A00428164%21RIV15-GA0-67985823/
n6http://linked.opendata.cz/resource/domain/vavai/projekt/
n4http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n15http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n8http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n10http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n18http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n16http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n12http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n14http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n11http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n5http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F14%3A00428164%21RIV15-GA0-67985823
rdf:type
skos:Concept n15:Vysledek
dcterms:description
Mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH) and succinate dehydrogenase (SDH) are important source of reactive oxygen species (ROS), but the mechanism of their production is still poorly understood. In this study we demonstrate two distinct mechanisms, with flavin being the most likely source of electron leak in SDH and coenzyme Q site in mGPDH. Furthermore, mGPDH was found to associate into homooligomers and supercomplexes capable to produce ROS similarly as the isolated enzyme itself Mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH) and succinate dehydrogenase (SDH) are important source of reactive oxygen species (ROS), but the mechanism of their production is still poorly understood. In this study we demonstrate two distinct mechanisms, with flavin being the most likely source of electron leak in SDH and coenzyme Q site in mGPDH. Furthermore, mGPDH was found to associate into homooligomers and supercomplexes capable to produce ROS similarly as the isolated enzyme itself
dcterms:title
ROS generation and multiple forms of mammalian mitochondrial glycerol-3-phosphate dehydrogenase ROS generation and multiple forms of mammalian mitochondrial glycerol-3-phosphate dehydrogenase
skos:prefLabel
ROS generation and multiple forms of mammalian mitochondrial glycerol-3-phosphate dehydrogenase ROS generation and multiple forms of mammalian mitochondrial glycerol-3-phosphate dehydrogenase
skos:notation
RIV/67985823:_____/14:00428164!RIV15-GA0-67985823
n3:aktivita
n16:P n16:I
n3:aktivity
I, P(GPP303/10/P227), P(LL1204)
n3:cisloPeriodika
1
n3:dodaniDat
n5:2015
n3:domaciTvurceVysledku
n4:1407953 n4:9734481 n4:8943222 n4:8507813 n4:1104330 n4:9418792 n4:9705325
n3:druhVysledku
n14:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n7:predkladatel
n3:idSjednocenehoVysledku
43285
n3:idVysledku
RIV/67985823:_____/14:00428164
n3:jazykVysledku
n12:eng
n3:klicovaSlova
mitochondrial glycerol-3-phosphate dehydrogenase; ROS production; supercomplex; in-gel ROS detection
n3:klicoveSlovo
n10:mitochondrial%20glycerol-3-phosphate%20dehydrogenase n10:ROS%20production n10:in-gel%20ROS%20detection n10:supercomplex
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[DEFEED7F3745]
n3:nazevZdroje
Biochimica Et Biophysica Acta-Bioenergetics
n3:obor
n11:EB
n3:pocetDomacichTvurcuVysledku
7
n3:pocetTvurcuVysledku
7
n3:projekt
n6:GPP303%2F10%2FP227 n6:LL1204
n3:rokUplatneniVysledku
n5:2014
n3:svazekPeriodika
1837
n3:tvurceVysledku
Mráček, Tomáš Houštěk, Josef Kovářová, Nikola Holzerová, Eliška Vrbacký, Marek Ješina, Pavel Drahota, Zdeněk
n3:wos
000328724800009
s:issn
0005-2728
s:numberOfPages
14
n8:doi
10.1016/j.bbabio.2013.08.007