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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F14%3A00428048%21RIV15-GA0-67985823
rdf:type
skos:Concept n11:Vysledek
dcterms:description
The activation of calcium-dependent chloride channels during norepinephrine-induced contraction of vascular smooth muscle was suggested to depolarize cell membrane and to increase calcium entry. Hypertension and ageing are associated with altered calcium handling including possible activation of calcium-dependent chloride channels. Our study was aimed to determine calcium -dependent chloride channels contribution to norepinephrine-induced contraction during hypertension and ageing. We have found that contribution of calcium -dependent chloride channels to norepinephrine-induced contraction diminished with age, hypertension development, and/or NO synthesis inhibition The activation of calcium-dependent chloride channels during norepinephrine-induced contraction of vascular smooth muscle was suggested to depolarize cell membrane and to increase calcium entry. Hypertension and ageing are associated with altered calcium handling including possible activation of calcium-dependent chloride channels. Our study was aimed to determine calcium -dependent chloride channels contribution to norepinephrine-induced contraction during hypertension and ageing. We have found that contribution of calcium -dependent chloride channels to norepinephrine-induced contraction diminished with age, hypertension development, and/or NO synthesis inhibition
dcterms:title
Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing
skos:prefLabel
Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing
skos:notation
RIV/67985823:_____/14:00428048!RIV15-GA0-67985823
n3:aktivita
n14:P n14:I
n3:aktivity
I, P(GAP304/12/0259)
n3:cisloPeriodika
2014
n3:dodaniDat
n6:2015
n3:domaciTvurceVysledku
n8:1229109 n8:1477498 Behuliak, Michal n8:1413201
n3:druhVysledku
n17:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
8820
n3:idVysledku
RIV/67985823:_____/14:00428048
n3:jazykVysledku
n10:eng
n3:klicovaSlova
calcium-dependent chloride channels; endothelium-derived contracting factor; ageing
n3:klicoveSlovo
n4:endothelium-derived%20contracting%20factor n4:ageing n4:calcium-dependent%20chloride%20channels
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[6711CB378D90]
n3:nazevZdroje
BioMed Research International
n3:obor
n15:FA
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
5
n3:projekt
n9:GAP304%2F12%2F0259
n3:rokUplatneniVysledku
n6:2014
n3:svazekPeriodika
2014
n3:tvurceVysledku
Karen, Petr Behuliak, Michal Zicha, Josef Líšková, Silvia Petrová, M.
n3:wos
000332565500001
s:issn
2314-6133
s:numberOfPages
9
n12:doi
10.1155/2014/289361