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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F13%3A00397537%21RIV14-GA0-67985823
rdf:type
skos:Concept n17:Vysledek
dcterms:description
We showed that two consecutive square-wave temperature cycles with amplitudes of 2.5°C are with similar efficiency able to restart damped oscillations and entrain the circadian clock in fibroblasts derived from both spontaneously hypertensive rat and control Wistar rat. We described phase response curves to temperature cycles for fibroblast clock from both strains and concluded that despite slight resistance of SHR cells to temperature entrainment, the overall effect is too weak to be responsible for SHR circadian phenotype in vivo We showed that two consecutive square-wave temperature cycles with amplitudes of 2.5°C are with similar efficiency able to restart damped oscillations and entrain the circadian clock in fibroblasts derived from both spontaneously hypertensive rat and control Wistar rat. We described phase response curves to temperature cycles for fibroblast clock from both strains and concluded that despite slight resistance of SHR cells to temperature entrainment, the overall effect is too weak to be responsible for SHR circadian phenotype in vivo
dcterms:title
Entrainment of Spontaneously Hypertensive Rat Fibroblasts by Temperature Cycles Entrainment of Spontaneously Hypertensive Rat Fibroblasts by Temperature Cycles
skos:prefLabel
Entrainment of Spontaneously Hypertensive Rat Fibroblasts by Temperature Cycles Entrainment of Spontaneously Hypertensive Rat Fibroblasts by Temperature Cycles
skos:notation
RIV/67985823:_____/13:00397537!RIV14-GA0-67985823
n17:predkladatel
n18:ico%3A67985823
n3:aktivita
n15:I n15:P
n3:aktivity
I, P(GAP303/11/0668), P(GPP305/10/P244)
n3:cisloPeriodika
10
n3:dodaniDat
n4:2014
n3:domaciTvurceVysledku
n9:2737639 n9:9567801
n3:druhVysledku
n14:J
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
73000
n3:idVysledku
RIV/67985823:_____/13:00397537
n3:jazykVysledku
n8:eng
n3:klicovaSlova
circadian rhythms; temperature; entrainment; SHR; fibroblasts; phase response curve
n3:klicoveSlovo
n11:entrainment n11:fibroblasts n11:temperature n11:circadian%20rhythms n11:SHR n11:phase%20response%20curve
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[D57006E86467]
n3:nazevZdroje
PLoS ONE
n3:obor
n13:EB
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
2
n3:projekt
n12:GAP303%2F11%2F0668 n12:GPP305%2F10%2FP244
n3:rokUplatneniVysledku
n4:2013
n3:svazekPeriodika
8
n3:tvurceVysledku
Sládek, Martin Sumová, Alena
n3:wos
000325501300112
s:issn
1932-6203
s:numberOfPages
10
n10:doi
10.1371/journal.pone.0077010