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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F12%3A00388553%21RIV13-GA0-67985823
rdf:type
skos:Concept n5:Vysledek
dcterms:description
Our data indicate the significant intrinsic efficacy of GABAB-receptors in rat brain cortex already at birth (PD1, PD2). The potency of G-protein response to baclofen (characterized by EC50 values) was also high at birth but unchanged by further postnatal development. The highest plasma membrane density of GABAB-R was measured in 1-day old animals Our data indicate the significant intrinsic efficacy of GABAB-receptors in rat brain cortex already at birth (PD1, PD2). The potency of G-protein response to baclofen (characterized by EC50 values) was also high at birth but unchanged by further postnatal development. The highest plasma membrane density of GABAB-R was measured in 1-day old animals
dcterms:title
Ontogenetic Development of GABA(B)-Receptor Signaling Cascade in Plasma Membranes Isolated From Rat Brain Cortex; the Number of GABA(B)-Receptors Is High Already Shortly After the Birth Ontogenetic Development of GABA(B)-Receptor Signaling Cascade in Plasma Membranes Isolated From Rat Brain Cortex; the Number of GABA(B)-Receptors Is High Already Shortly After the Birth
skos:prefLabel
Ontogenetic Development of GABA(B)-Receptor Signaling Cascade in Plasma Membranes Isolated From Rat Brain Cortex; the Number of GABA(B)-Receptors Is High Already Shortly After the Birth Ontogenetic Development of GABA(B)-Receptor Signaling Cascade in Plasma Membranes Isolated From Rat Brain Cortex; the Number of GABA(B)-Receptors Is High Already Shortly After the Birth
skos:notation
RIV/67985823:_____/12:00388553!RIV13-GA0-67985823
n5:predkladatel
n6:ico%3A67985823
n3:aktivita
n15:Z n15:P n15:I
n3:aktivity
I, P(GAP207/12/0919), P(GBP304/12/G069), Z(AV0Z50110509)
n3:cisloPeriodika
6
n3:dodaniDat
n8:2013
n3:domaciTvurceVysledku
Kagan, Dmytro n14:9531238 n14:3710769 n14:7326718
n3:druhVysledku
n19:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
156587
n3:idVysledku
RIV/67985823:_____/12:00388553
n3:jazykVysledku
n9:eng
n3:klicovaSlova
postnatal development; GABAB-receptors; G-protein coupling/activation; baclofen; SKF97541
n3:klicoveSlovo
n4:postnatal%20development n4:G-protein%20coupling%2Factivation n4:GABAB-receptors n4:SKF97541 n4:baclofen
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[AA9938EEBFBA]
n3:nazevZdroje
Physiological Research
n3:obor
n11:CE
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:projekt
n10:GBP304%2F12%2FG069 n10:GAP207%2F12%2F0919
n3:rokUplatneniVysledku
n8:2012
n3:svazekPeriodika
61
n3:tvurceVysledku
Dlouhá, Kateřina Roubalová, Lenka Svoboda, Petr Kagan, Dmytro
n3:wos
000314138600008
n3:zamer
n13:AV0Z50110509
s:issn
0862-8408
s:numberOfPages
7