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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F12%3A00387974%21RIV13-TA0-67985823
rdf:type
skos:Concept n8:Vysledek
dcterms:description
Photodynamic therapy (PDT) is a clinically-accepted approach for the therapy of many types of cancer. This study focused on the treatment of mammarian carcinoma by topical administration of hydroxyl-aluminium phthalocyanine (AlOH-PC), compared to a clinically approved photosensitizer. Therapeutic studies revealed that AlOH-PC treatment led to complete tumour remission in 90% of experimental animals, whereas usage of the commercially available Metvix only postponed the tumour growth. Moreover, usage of liposomal AlOH-PC shortened the time allowed between the application of the photosensitizer and light exposure Photodynamic therapy (PDT) is a clinically-accepted approach for the therapy of many types of cancer. This study focused on the treatment of mammarian carcinoma by topical administration of hydroxyl-aluminium phthalocyanine (AlOH-PC), compared to a clinically approved photosensitizer. Therapeutic studies revealed that AlOH-PC treatment led to complete tumour remission in 90% of experimental animals, whereas usage of the commercially available Metvix only postponed the tumour growth. Moreover, usage of liposomal AlOH-PC shortened the time allowed between the application of the photosensitizer and light exposure
dcterms:title
Evaluation of Topical Photodynamic Therapy of Mammary Carcinoma with an Experimental Gel Containing Liposomal Hydroxyl-aluminium Phthalocyanine Evaluation of Topical Photodynamic Therapy of Mammary Carcinoma with an Experimental Gel Containing Liposomal Hydroxyl-aluminium Phthalocyanine
skos:prefLabel
Evaluation of Topical Photodynamic Therapy of Mammary Carcinoma with an Experimental Gel Containing Liposomal Hydroxyl-aluminium Phthalocyanine Evaluation of Topical Photodynamic Therapy of Mammary Carcinoma with an Experimental Gel Containing Liposomal Hydroxyl-aluminium Phthalocyanine
skos:notation
RIV/67985823:_____/12:00387974!RIV13-TA0-67985823
n8:predkladatel
n9:ico%3A67985823
n4:aktivita
n18:I n18:S n18:P n18:V n18:Z
n4:aktivity
I, P(2A-1TP1/026), P(OE09026), P(TA01010781), S, V, Z(AV0Z50110509)
n4:cisloPeriodika
9
n4:dodaniDat
n6:2013
n4:domaciTvurceVysledku
n14:1305476 n14:9322604
n4:druhVysledku
n17:J
n4:duvernostUdaju
n7:S
n4:entitaPredkladatele
n16:predkladatel
n4:idSjednocenehoVysledku
135228
n4:idVysledku
RIV/67985823:_____/12:00387974
n4:jazykVysledku
n15:eng
n4:klicovaSlova
photodynamic therapy; phthalocyanine; liposomal sensitizer
n4:klicoveSlovo
n11:liposomal%20sensitizer n11:photodynamic%20therapy n11:phthalocyanine
n4:kodStatuVydavatele
GR - Řecká republika
n4:kontrolniKodProRIV
[99865A674919]
n4:nazevZdroje
Anticancer Research
n4:obor
n13:FR
n4:pocetDomacichTvurcuVysledku
2
n4:pocetTvurcuVysledku
8
n4:projekt
n5:TA01010781 n5:OE09026 n5:2A-1TP1%2F026
n4:rokUplatneniVysledku
n6:2012
n4:svazekPeriodika
32
n4:tvurceVysledku
Horák, L. Poučková, P. Beneš, J. Zadinová, M. Ježek, Petr Větvička, D. Sutoris, K. Nekvasil, Miloš
n4:wos
000309243200022
n4:zamer
n19:AV0Z50110509
s:issn
0250-7005
s:numberOfPages
6