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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F12%3A00380083%21RIV13-MZ0-67985823
rdf:type
skos:Concept n14:Vysledek
dcterms:description
We describe a new method for the analysis of mitochondrial swelling curves. Using classical swelling curves, only the maximum extent of the swelling can be calculated in a numerical form. However, taking the derivative of the classical swelling curves enables the evaluation of two additional parameters of the swelling process in a numerical form, namely, the maximum swelling rate after the addition of the swelling inducer and the time at which the maximum swelling rate after the addition of the swelling inducer is obtained. The use of these three parameters enables the better characterization of the swelling process as demonstrated by the evaluation of calcium and phosphate interactions in the opening of the mitochondrial permeability transition pore and by the characterization of the peroxide We describe a new method for the analysis of mitochondrial swelling curves. Using classical swelling curves, only the maximum extent of the swelling can be calculated in a numerical form. However, taking the derivative of the classical swelling curves enables the evaluation of two additional parameters of the swelling process in a numerical form, namely, the maximum swelling rate after the addition of the swelling inducer and the time at which the maximum swelling rate after the addition of the swelling inducer is obtained. The use of these three parameters enables the better characterization of the swelling process as demonstrated by the evaluation of calcium and phosphate interactions in the opening of the mitochondrial permeability transition pore and by the characterization of the peroxide
dcterms:title
Characterization of calcium, phosphate and peroxide interactions in activation of mitochondrial swelling using derivative of the swelling curves Characterization of calcium, phosphate and peroxide interactions in activation of mitochondrial swelling using derivative of the swelling curves
skos:prefLabel
Characterization of calcium, phosphate and peroxide interactions in activation of mitochondrial swelling using derivative of the swelling curves Characterization of calcium, phosphate and peroxide interactions in activation of mitochondrial swelling using derivative of the swelling curves
skos:notation
RIV/67985823:_____/12:00380083!RIV13-MZ0-67985823
n14:predkladatel
n15:ico%3A67985823
n4:aktivita
n19:I n19:P
n4:aktivity
I, P(GP305/09/P145), P(NT12370)
n4:cisloPeriodika
3
n4:dodaniDat
n12:2013
n4:domaciTvurceVysledku
n11:8507813 n11:7362986
n4:druhVysledku
n18:J
n4:duvernostUdaju
n17:S
n4:entitaPredkladatele
n7:predkladatel
n4:idSjednocenehoVysledku
126802
n4:idVysledku
RIV/67985823:_____/12:00380083
n4:jazykVysledku
n5:eng
n4:klicovaSlova
mitochondrial swelling; mitochondrial permeability transition pore; Calcium, phosphate and peroxide interactions
n4:klicoveSlovo
n9:phosphate%20and%20peroxide%20interactions n9:mitochondrial%20swelling n9:mitochondrial%20permeability%20transition%20pore n9:Calcium
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[ED7A2B7DEC8F]
n4:nazevZdroje
Journal of Bioenergetics and Biomembranes
n4:obor
n13:FG
n4:pocetDomacichTvurcuVysledku
2
n4:pocetTvurcuVysledku
6
n4:projekt
n16:NT12370 n16:GP305%2F09%2FP145
n4:rokUplatneniVysledku
n12:2012
n4:svazekPeriodika
44
n4:tvurceVysledku
Drahota, Zdeněk Červinková, Z. Rychtrmoc, D. Endlicher, R. Staňková, P. Milerová, Marie
n4:wos
000304613700002
s:issn
0145-479X
s:numberOfPages
7
n10:doi
10.1007/s10863-012-9443-2