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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F12%3A00377147%21RIV13-AV0-67985823
rdf:type
skos:Concept n15:Vysledek
dcterms:description
Differentiation and metabolism of adipose tissue are modulated by thyroid hormones (THs), but relatively little is known about the metabolism of THs in this tissue. Our results document increased D1 gene expression and activity in adipose tissue of obese humans and suggest a role of 3,5,30-triiodo-L-thyronine formed by D1 in response to leptin in the modulation of adipose tissue metabolism Differentiation and metabolism of adipose tissue are modulated by thyroid hormones (THs), but relatively little is known about the metabolism of THs in this tissue. Our results document increased D1 gene expression and activity in adipose tissue of obese humans and suggest a role of 3,5,30-triiodo-L-thyronine formed by D1 in response to leptin in the modulation of adipose tissue metabolism
dcterms:title
Type I iodothyronine 5-deiodinase mRNA and activity is increased in adipose tissue of obese subjects Type I iodothyronine 5-deiodinase mRNA and activity is increased in adipose tissue of obese subjects
skos:prefLabel
Type I iodothyronine 5-deiodinase mRNA and activity is increased in adipose tissue of obese subjects Type I iodothyronine 5-deiodinase mRNA and activity is increased in adipose tissue of obese subjects
skos:notation
RIV/67985823:_____/12:00377147!RIV13-AV0-67985823
n15:predkladatel
n16:ico%3A67985823
n4:aktivita
n6:P n6:Z
n4:aktivity
P(OC08008), Z(AV0Z50110509), Z(MSM0021622413)
n4:cisloPeriodika
2
n4:dodaniDat
n12:2013
n4:domaciTvurceVysledku
n14:8278830 n14:5972450
n4:druhVysledku
n20:J
n4:duvernostUdaju
n17:S
n4:entitaPredkladatele
n8:predkladatel
n4:idSjednocenehoVysledku
175530
n4:idVysledku
RIV/67985823:_____/12:00377147
n4:jazykVysledku
n10:eng
n4:klicovaSlova
adipose tissue; thyroid hormones; deiodinases; tissue expression; enzyme activity
n4:klicoveSlovo
n9:enzyme%20activity n9:deiodinases n9:adipose%20tissue n9:thyroid%20hormones n9:tissue%20expression
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[A656C12D052E]
n4:nazevZdroje
International Journal of Obesity
n4:obor
n11:FB
n4:pocetDomacichTvurcuVysledku
2
n4:pocetTvurcuVysledku
7
n4:projekt
n19:OC08008
n4:rokUplatneniVysledku
n12:2012
n4:svazekPeriodika
36
n4:tvurceVysledku
Pavelka, S. Ortega, F. J. Jílková, Zuzana Moreno-Navarrete, J. M. Kopecký, Jan Fernández-Real, J. M. Rodriguez-Hermosa, J. I.
n4:wos
000300321600019
n4:zamer
n5:AV0Z50110509 n5:MSM0021622413
s:issn
0307-0565
s:numberOfPages
5
n18:doi
10.1038/ijo.2011.101