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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F11%3A00365082%21RIV12-AV0-67985823
rdf:type
n3:Vysledek skos:Concept
dcterms:description
In our study, we present a novel p(chi2) (chi-square) method for evaluating the anisotropy of line systems that involves comparing the observed length densities of lines with the discrete uniform distribution of an isotropic line system with the chi2-test. Using this method in our open source software, we determined the rose of directions, preferential directions and level of anisotropy of linear systems representing the microscopic blood vessels in samples of various regions from human brains (cortex, subcortical gray matter and white matter). The novel method was compared with two other methods used for anisotropy quantification (ellipsoidal and fractional anisotropy). All three methods detected different levels of anisotropy of blood microvessels in human brain. The microvascular bed in the cortex was closer to an isotropic network, while the microvessels supplying the white matter appeared to be an anisotropic and direction-sensitive system In our study, we present a novel p(chi2) (chi-square) method for evaluating the anisotropy of line systems that involves comparing the observed length densities of lines with the discrete uniform distribution of an isotropic line system with the chi2-test. Using this method in our open source software, we determined the rose of directions, preferential directions and level of anisotropy of linear systems representing the microscopic blood vessels in samples of various regions from human brains (cortex, subcortical gray matter and white matter). The novel method was compared with two other methods used for anisotropy quantification (ellipsoidal and fractional anisotropy). All three methods detected different levels of anisotropy of blood microvessels in human brain. The microvascular bed in the cortex was closer to an isotropic network, while the microvessels supplying the white matter appeared to be an anisotropic and direction-sensitive system
dcterms:title
How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels
skos:prefLabel
How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels How to asses, visualize and compare the anisotropy of linear structures reconstructed from optical sections ? A study based on histopathological quantification of human brain microvessels
skos:notation
RIV/67985823:_____/11:00365082!RIV12-AV0-67985823
n3:predkladatel
n12:ico%3A67985823
n4:aktivita
n20:O n20:P n20:Z
n4:aktivity
O, P(ED1.1.00/02.0090), P(GA106/09/0740), P(GP106/09/P226), Z(AV0Z50110509)
n4:cisloPeriodika
-
n4:dodaniDat
n11:2012
n4:domaciTvurceVysledku
n14:4096193
n4:druhVysledku
n15:J
n4:duvernostUdaju
n7:S
n4:entitaPredkladatele
n5:predkladatel
n4:idSjednocenehoVysledku
202810
n4:idVysledku
RIV/67985823:_____/11:00365082
n4:jazykVysledku
n16:eng
n4:klicovaSlova
rose of directions; preferential directions; chi-square test; length density; python
n4:klicoveSlovo
n8:python n8:rose%20of%20directions n8:chi-square%20test n8:preferential%20directions n8:length%20density
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[202314823309]
n4:nazevZdroje
Journal of Theoretical Biology
n4:obor
n17:EA
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
5
n4:projekt
n13:GA106%2F09%2F0740 n13:ED1.1.00%2F02.0090 n13:GP106%2F09%2FP226
n4:rokUplatneniVysledku
n11:2011
n4:svazekPeriodika
286
n4:tvurceVysledku
Tonar, Z. Janáček, Jiří Kochová, P. Witter, K. Cimrman, R.
n4:wos
000294975800008
n4:zamer
n19:AV0Z50110509
s:issn
0022-5193
s:numberOfPages
12
n18:doi
10.1016/j.jtbi.2011.07.004