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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F11%3A00358902%21RIV12-MZ0-67985823
rdf:type
n5:Vysledek skos:Concept
dcterms:description
We sought to investigate whether increased levels of human CRP, per se, can promote increases in blood pressure and disturbances in glucose and lipid metabolism characteristic of the metabolic syndrome. To accomplish this goal, we transgenically expressed human CRP in the spontaneously hypertensive rat (SHR) and found that that increased CRP is more than just a marker of inflammation and can directly promote multiple features of the metabolic syndrome We sought to investigate whether increased levels of human CRP, per se, can promote increases in blood pressure and disturbances in glucose and lipid metabolism characteristic of the metabolic syndrome. To accomplish this goal, we transgenically expressed human CRP in the spontaneously hypertensive rat (SHR) and found that that increased CRP is more than just a marker of inflammation and can directly promote multiple features of the metabolic syndrome
dcterms:title
Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome
skos:prefLabel
Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome Effects of Human C-Reactive Protein on Pathogenesis of Features of the Metabolic Syndrome
skos:notation
RIV/67985823:_____/11:00358902!RIV12-MZ0-67985823
n5:predkladatel
n19:ico%3A67985823
n3:aktivita
n9:P n9:Z
n3:aktivity
P(1M0520), P(GAP301/10/0290), P(GAP303/10/0505), P(IAA500110805), P(ME08006), P(NS9757), P(NS9759), Z(AV0Z50110509), Z(MSM6046070901)
n3:cisloPeriodika
4
n3:dodaniDat
n17:2012
n3:domaciTvurceVysledku
n12:9889140 n12:9002553 n12:9418725 n12:1168207 n12:7350325 n12:2655586
n3:druhVysledku
n4:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
196640
n3:idVysledku
RIV/67985823:_____/11:00358902
n3:jazykVysledku
n20:eng
n3:klicovaSlova
C-reactive protein; metabolic syndrome; transgenic rat
n3:klicoveSlovo
n14:metabolic%20syndrome n14:transgenic%20rat n14:C-reactive%20protein
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[F63C631A2FA3]
n3:nazevZdroje
Hypertension
n3:obor
n8:FB
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
13
n3:projekt
n16:NS9757 n16:NS9759 n16:IAA500110805 n16:GAP303%2F10%2F0505 n16:GAP301%2F10%2F0290 n16:1M0520 n16:ME08006
n3:rokUplatneniVysledku
n17:2011
n3:svazekPeriodika
57
n3:tvurceVysledku
Landa, Vladimír Mlejnek, Petr Fan, J. Šilhavý, Jan Kazdová, L. Oliyarnyk, O. Wang, J. Malínská, H. Kurtz, T. W. Pravenec, Michal Šimáková, Miroslava Kajiya, T. Zídek, Václav
n3:wos
000288434600019
n3:zamer
n10:MSM6046070901 n10:AV0Z50110509
s:issn
0194-911X
s:numberOfPages
7
n18:doi
10.1161/HYPERTENSIONAHA.110.164350