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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F10%3A00355652%21RIV11-MSM-67985823
rdf:type
n7:Vysledek skos:Concept
dcterms:description
C. glabrata cnh1 and ena1 mutant strains lacking the alkali-metal-cation exporters encoded by ENA1 and CNH1 genes have been constructed. All genes have been substituted by the Nourseothricin cassette. Finally, the cassettes were excised using a recombinase and leaving a single FRT site in the loci. Unique GMO strains in the C. glabrata background have been created to study the role of alkali-metal-cation exporters in yeast pathogenicity and virulence C. glabrata cnh1 and ena1 mutant strains lacking the alkali-metal-cation exporters encoded by ENA1 and CNH1 genes have been constructed. All genes have been substituted by the Nourseothricin cassette. Finally, the cassettes were excised using a recombinase and leaving a single FRT site in the loci. Unique GMO strains in the C. glabrata background have been created to study the role of alkali-metal-cation exporters in yeast pathogenicity and virulence
dcterms:title
Genetically modified Candida glabrata strains lacking plasma membrane efflux systems for potassium and podium cations Genetically modified Candida glabrata strains lacking plasma membrane efflux systems for potassium and podium cations
skos:prefLabel
Genetically modified Candida glabrata strains lacking plasma membrane efflux systems for potassium and podium cations Genetically modified Candida glabrata strains lacking plasma membrane efflux systems for potassium and podium cations
skos:notation
RIV/67985823:_____/10:00355652!RIV11-MSM-67985823
n3:aktivita
n4:P n4:Z
n3:aktivity
P(LC531), Z(AV0Z50110509)
n3:dodaniDat
n14:2011
n3:domaciTvurceVysledku
n12:9978194 n12:2335042
n3:druhVysledku
n19:G%2FB
n3:duvernostUdaju
n16:S
n3:ekonomickeParametry
náklady v 300 000,- Kč, licenční poplatek 50 000,- Kč
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
260424
n3:idVysledku
RIV/67985823:_____/10:00355652
n3:interniIdentifikace
C. glabrata ena1 a cnh1
n3:jazykVysledku
n6:eng
n3:kategorie
n20:A
n3:klicovaSlova
Candia glabrata; salt-sensitive mutant
n3:klicoveSlovo
n9:Candia%20glabrata n9:salt-sensitive%20mutant
n3:kontrolniKodProRIV
[05D8A6FC8DDC]
n3:licencniPoplatek
n11:N
n3:lokalizaceVysledku
Fyziologický ústav AV ČR v.v
n3:obor
n13:EE
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
2
n3:projekt
n5:LC531
n3:rokUplatneniVysledku
n14:2010
n3:technickeParametry
Mutantní kmeny C. glabrata s vysokou citlivostí k solím alkalických kovů vhodné studium vlivu transportérů na virulenci a pro screening nových látek s antifungálním účinkem
n3:tvurceVysledku
Sychrová, Hana Krauke, Yannick
n3:vlastnik
n10:vlastnikVysledku
n3:vyuzitiJinymSubjektem
n17:P
n3:zamer
n18:AV0Z50110509