This HTML5 document contains 39 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n10http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n7http://linked.opendata.cz/resource/domain/vavai/projekt/
n15http://linked.opendata.cz/ontology/domain/vavai/
n18http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
n5http://linked.opendata.cz/ontology/domain/vavai/riv/
skoshttp://www.w3.org/2004/02/skos/core#
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n6http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n14http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n12http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F67985823%3A_____%2F10%3A00348428%21RIV11-GA0-67985823/
n17http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n8http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n11http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n16http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F10%3A00348428%21RIV11-GA0-67985823
rdf:type
skos:Concept n15:Vysledek
dcterms:description
This review summarizes over 30 years of reserch on the molecular mechanisms of allosteric interactions of drugs with the receptor and for new allosteric modulators of muscarinic receptors with potential therapeutic use. Identification of positive modulators of acetylcholine binding and function that enhance neurotransmission and the discovery of highly selective allosteric modulators are mile-stones on the way to novel therapeutic agents for the treatment of schizophrenia, Alzheimer´s disease and other involving impaired cognitive function This review summarizes over 30 years of reserch on the molecular mechanisms of allosteric interactions of drugs with the receptor and for new allosteric modulators of muscarinic receptors with potential therapeutic use. Identification of positive modulators of acetylcholine binding and function that enhance neurotransmission and the discovery of highly selective allosteric modulators are mile-stones on the way to novel therapeutic agents for the treatment of schizophrenia, Alzheimer´s disease and other involving impaired cognitive function
dcterms:title
Allosteric Modulation of Muscarinic Acetylcholine Receptors Allosteric Modulation of Muscarinic Acetylcholine Receptors
skos:prefLabel
Allosteric Modulation of Muscarinic Acetylcholine Receptors Allosteric Modulation of Muscarinic Acetylcholine Receptors
skos:notation
RIV/67985823:_____/10:00348428!RIV11-GA0-67985823
n5:aktivita
n8:P n8:Z
n5:aktivity
P(GA305/09/0681), Z(AV0Z50110509)
n5:cisloPeriodika
9
n5:dodaniDat
n16:2011
n5:domaciTvurceVysledku
n10:8826897
n5:druhVysledku
n11:J
n5:duvernostUdaju
n14:S
n5:entitaPredkladatele
n12:predkladatel
n5:idSjednocenehoVysledku
245991
n5:idVysledku
RIV/67985823:_____/10:00348428
n5:jazykVysledku
n17:eng
n5:klicovaSlova
muscarinic acetylcholine receptors; allosteric modulation; Alzheimer´s disease
n5:klicoveSlovo
n6:Alzheimer%C2%B4s%20disease n6:muscarinic%20acetylcholine%20receptors n6:allosteric%20modulation
n5:kodStatuVydavatele
CH - Švýcarská konfederace
n5:kontrolniKodProRIV
[F23BBA25621C]
n5:nazevZdroje
Pharmaceuticals
n5:obor
n13:CE
n5:pocetDomacichTvurcuVysledku
1
n5:pocetTvurcuVysledku
2
n5:projekt
n7:GA305%2F09%2F0681
n5:rokUplatneniVysledku
n16:2010
n5:svazekPeriodika
3
n5:tvurceVysledku
El-Fakahany, E. E. Jakubík, Jan
n5:zamer
n18:AV0Z50110509
s:issn
1424-8247
s:numberOfPages
23