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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F10%3A00344033%21RIV11-AV0-67985823
rdf:type
n6:Vysledek skos:Concept
dcterms:description
Endothelial population changes in hippocampal microvessels exposed to 56Fe ions at doses of 0, 0.5, 2 and 4 Gy were quantified using unbiased stereological techniques. Twelve months after exposure, mice that received 0.5 Gy or 2 Gy of iron ions showed a 34% or 29% loss of endothelial cells, respectively, in the hippocampal cornu ammonis region 1 (CA1) compared to age-matched controls or mice that received 4 Gy. In contrast to the CA1, in the dentate gyrus (DG), there was no significant difference in microvessel cell and length density between irradiated groups and age-matched controls. Vascular topology differences between CA1 and DG may account for the variation in dose response Endothelial population changes in hippocampal microvessels exposed to 56Fe ions at doses of 0, 0.5, 2 and 4 Gy were quantified using unbiased stereological techniques. Twelve months after exposure, mice that received 0.5 Gy or 2 Gy of iron ions showed a 34% or 29% loss of endothelial cells, respectively, in the hippocampal cornu ammonis region 1 (CA1) compared to age-matched controls or mice that received 4 Gy. In contrast to the CA1, in the dentate gyrus (DG), there was no significant difference in microvessel cell and length density between irradiated groups and age-matched controls. Vascular topology differences between CA1 and DG may account for the variation in dose response
dcterms:title
High-LET Radiation-Induced Response of Microvessels in the Hippocampus High-LET Radiation-Induced Response of Microvessels in the Hippocampus
skos:prefLabel
High-LET Radiation-Induced Response of Microvessels in the Hippocampus High-LET Radiation-Induced Response of Microvessels in the Hippocampus
skos:notation
RIV/67985823:_____/10:00344033!RIV11-AV0-67985823
n3:aktivita
n8:Z
n3:aktivity
Z(AV0Z50110509)
n3:cisloPeriodika
4
n3:dodaniDat
n11:2011
n3:domaciTvurceVysledku
n15:6691587
n3:druhVysledku
n9:J
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
261571
n3:idVysledku
RIV/67985823:_____/10:00344033
n3:jazykVysledku
n17:eng
n3:klicovaSlova
hippocampus; stereology; microvessels
n3:klicoveSlovo
n16:stereology n16:microvessels n16:hippocampus
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[1E78309BD600]
n3:nazevZdroje
Radiation Research
n3:obor
n14:EA
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
10
n3:rokUplatneniVysledku
n11:2010
n3:svazekPeriodika
173
n3:tvurceVysledku
Kubínová, Lucie Nelson, G. A. Rightnar, S. Fike, J. R. Favre, C. J. Smith, A. Campbell-Beachler, M. Mao, X. W. Anderson, E. Jones, T.
n3:wos
276472800011
n3:zamer
n12:AV0Z50110509
s:issn
0033-7587
s:numberOfPages
8