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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F07%3A00331650%21RIV10-MSM-67985823
rdf:type
n11:Vysledek skos:Concept
dcterms:description
The effect of thiazide-like diuretic-indapamide on fibrosis development in the left ventricle of young spontaneously hypertensive rats (SHR) was studied in order to assess the involvement of nitric oxide in this process. Indapamide prevented myocardial fibrosis development in SHR, but without affecting collagen type I to type III ratio. Indapamide did not affect NOS activity as well as eNOS and iNOS protein expressions in the left ventricles. Thus indapamide-induced prevention of myocardial fibrosis is not mediated by nitric oxide-related mechanism The effect of thiazide-like diuretic-indapamide on fibrosis development in the left ventricle of young spontaneously hypertensive rats (SHR) was studied in order to assess the involvement of nitric oxide in this process. Indapamide prevented myocardial fibrosis development in SHR, but without affecting collagen type I to type III ratio. Indapamide did not affect NOS activity as well as eNOS and iNOS protein expressions in the left ventricles. Thus indapamide-induced prevention of myocardial fibrosis is not mediated by nitric oxide-related mechanism
dcterms:title
Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related
skos:prefLabel
Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related
skos:notation
RIV/67985823:_____/07:00331650!RIV10-MSM-67985823
n3:aktivita
n6:Z n6:P
n3:aktivity
P(1M0510), Z(AV0Z50110509)
n3:cisloPeriodika
6
n3:dodaniDat
n7:2010
n3:domaciTvurceVysledku
n18:8274215
n3:druhVysledku
n10:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
425960
n3:idVysledku
RIV/67985823:_____/07:00331650
n3:jazykVysledku
n17:eng
n3:klicovaSlova
indapamide; myocardial fibrosis; genetic hypertension
n3:klicoveSlovo
n12:genetic%20hypertension n12:indapamide n12:myocardial%20fibrosis
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[CAE1BD45B86E]
n3:nazevZdroje
Physiological Research
n3:obor
n9:ED
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
5
n3:projekt
n13:1M0510
n3:rokUplatneniVysledku
n7:2007
n3:svazekPeriodika
56
n3:tvurceVysledku
Jendeková, L. Pecháňová, Olga Janega, P. Babál, P. Kojšová, S.
n3:wos
252358700020
n3:zamer
n8:AV0Z50110509
s:issn
0862-8408
s:numberOfPages
4