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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F07%3A00088967%21RIV08-AV0-67985823
rdf:type
n9:Vysledek skos:Concept
dcterms:description
Úkolem práce bylo přispět k odhalení úlohy inhibičních Gi proteinů a nifedipin-senzitivního influxu vápníku v alfa-adrenergní vazokonstrikci u WKY a SHR potkanů. Předchozí podání nifedipinu nebo PTX snížilo fenylefrinem- a klonidinem-vyvolanou tlakovou odpověď, změna byla větší u alfa 2-adrenergní vazokonstrikce. Naše výsledky naznačují že Gi proteiny a VDCC hrají důležitou roli v adrenergní vazokonstrikci This work was aimed to evaluate the role of inhibitory Gi proteins and nifedipine-sensitive calcium influx in alpha-adrenergic vasoconstriction in WKY and SHR rats.Pretreatment with nifedipine or PTX reduced both phenylephrine- and clonidine-induced blood pressure responses, the changes being greater on alpha 2-adrenergic vasoconstriction. Our results indicate that Gi proteins and VDCC play an important role in adrenergic vasoconstriction This work was aimed to evaluate the role of inhibitory Gi proteins and nifedipine-sensitive calcium influx in alpha-adrenergic vasoconstriction in WKY and SHR rats.Pretreatment with nifedipine or PTX reduced both phenylephrine- and clonidine-induced blood pressure responses, the changes being greater on alpha 2-adrenergic vasoconstriction. Our results indicate that Gi proteins and VDCC play an important role in adrenergic vasoconstriction
dcterms:title
In vivo effects of pertussis toxin on adrenergic vasoconstriction In vivo effects of pertussis toxin on adrenergic vasoconstriction In vivo účinek pertussis toxinu na adrenergní vazokonstrikci
skos:prefLabel
In vivo effects of pertussis toxin on adrenergic vasoconstriction In vivo effects of pertussis toxin on adrenergic vasoconstriction In vivo účinek pertussis toxinu na adrenergní vazokonstrikci
skos:notation
RIV/67985823:_____/07:00088967!RIV08-AV0-67985823
n5:strany
76;82
n5:aktivita
n17:P n17:Z
n5:aktivity
P(1M0510), Z(AV0Z50110509)
n5:dodaniDat
n8:2008
n5:domaciTvurceVysledku
n12:4935985 n12:2115557 n12:4463404 n12:1477498
n5:druhVysledku
n13:C
n5:duvernostUdaju
n6:S
n5:entitaPredkladatele
n18:predkladatel
n5:idSjednocenehoVysledku
425878
n5:idVysledku
RIV/67985823:_____/07:00088967
n5:jazykVysledku
n14:eng
n5:klicovaSlova
inhibitory Gi proteins; nifedipine-sensitive calcium influx; alpha-adrenergic vasoconstriction
n5:klicoveSlovo
n7:alpha-adrenergic%20vasoconstriction n7:inhibitory%20Gi%20proteins n7:nifedipine-sensitive%20calcium%20influx
n5:kontrolniKodProRIV
[EB362480EAA3]
n5:mistoVydani
Bratislava
n5:nazevZdroje
Nitric oxide signaling pathways
n5:obor
n10:FA
n5:pocetDomacichTvurcuVysledku
4
n5:pocetTvurcuVysledku
4
n5:projekt
n16:1M0510
n5:rokUplatneniVysledku
n8:2007
n5:tvurceVysledku
Kuneš, Jaroslav Pintérová, Mária Zicha, Josef Dobešová, Zdenka
n5:zamer
n15:AV0Z50110509
s:numberOfPages
7
n11:hasPublisher
Advent-Orion
n20:isbn
978-80-8071-094-1