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Statements

Subject Item
n2:RIV%2F67985823%3A_____%2F01%3A20010274%21RIV%2F2003%2FAV0%2FA20003%2FN
rdf:type
skos:Concept n10:Vysledek
dcterms:description
The ultrastructure of regenerating intrafusal and extrafusal fibres was studied 18 hours to 30 days after heterochronous isotransplantation, when bupivacaine-treated EDL or soleus muscles from early postnatal rats were intramuscularly grafted into EDL muscles of adult inbred recipients. Similarly as in other models of mammalian muscle regeneration, surviving satellite cells gave rise to presumptive myoblasts multiplying within the preserved basal lamina tubes at day 4 after grafting, myoblasts fused to form myotubes with central myonuclei by day 6 after grafting. Extrafusal myotubes differentiated into thin muscle fibres by day 8, which progressively increased in diameter and their nuclei became localized subsarcolemmally from day 13 onwards. The basal laminae of some intrafusal fibres already contained one or more nascent myotubes by day 4 after grafting. Regenerated intrafusal fibres lacked the typical nuclear accumulations and their number varied from 1 to 8 fibres per spindle; additional fibres fo The ultrastructure of regenerating intrafusal and extrafusal fibres was studied 18 hours to 30 days after heterochronous isotransplantation, when bupivacaine-treated EDL or soleus muscles from early postnatal rats were intramuscularly grafted into EDL muscles of adult inbred recipients. Similarly as in other models of mammalian muscle regeneration, surviving satellite cells gave rise to presumptive myoblasts multiplying within the preserved basal lamina tubes at day 4 after grafting, myoblasts fused to form myotubes with central myonuclei by day 6 after grafting. Extrafusal myotubes differentiated into thin muscle fibres by day 8, which progressively increased in diameter and their nuclei became localized subsarcolemmally from day 13 onwards. The basal laminae of some intrafusal fibres already contained one or more nascent myotubes by day 4 after grafting. Regenerated intrafusal fibres lacked the typical nuclear accumulations and their number varied from 1 to 8 fibres per spindle; additional fibres fo
dcterms:title
Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation. Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation.
skos:prefLabel
Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation. Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation.
skos:notation
RIV/67985823:_____/01:20010274!RIV/2003/AV0/A20003/N
n3:strany
473;484
n3:aktivita
n14:Z n14:P
n3:aktivity
P(GA304/00/1653), Z(AV0Z5011922)
n3:cisloPeriodika
5
n3:dodaniDat
n4:2003
n3:domaciTvurceVysledku
n13:9067280 n13:6371876
n3:druhVysledku
n16:J
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
678443
n3:idVysledku
RIV/67985823:_____/01:20010274
n3:jazykVysledku
n15:eng
n3:klicovaSlova
muscle transplantation; - degeneration and regeneration of muscle fibers; - extrafusal and intrafusal fibers
n3:klicoveSlovo
n8:-%20extrafusal%20and%20intrafusal%20fibers n8:muscle%20transplantation n8:-%20degeneration%20and%20regeneration%20of%20muscle%20fibers
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[1272B02C7850]
n3:nazevZdroje
Acta Neuropathologica
n3:obor
n18:FH
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
2
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n17:GA304%2F00%2F1653
n3:rokUplatneniVysledku
n4:2001
n3:svazekPeriodika
102
n3:tvurceVysledku
Jirmanová, Isa Soukup, Tomáš
n3:zamer
n5:AV0Z5011922
s:issn
0001-6322
s:numberOfPages
12