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Statements

Subject Item
n2:RIV%2F67985807%3A_____%2F09%3A00338859%21RIV10-AV0-67985807
rdf:type
n8:Vysledek skos:Concept
dcterms:description
Aim of the study was to investigate the relationship between the postseasonal increase in the concentration of leukotriene (LT) B4 and LTE4 in exhaled breath condensate (EBC) and bronchial responsiveness to methacholine (BRM) in patients with seasonal allergic rhinitis (SAR). In 28 patients with SAR and 50 healthy study patients, the leukotrienes were measured during and after the pollen season by gas chromatography/mass spectrometry. Following seasonal and postseasonal median values were measured in patients with SAR in comparison with control patients: LTB4: 131 and 90 pg/mL vs 80 and 79 pg/mL, P < .001 and P = .03, respectively; LTE4: 122 and 86 pg/mL vs 76 and 74 pg/mL, P < .001and P = .02, respectively. Five months after the pollen season, the concentrations of LTB4 and LTE4 decreased with respect to their seasonal values (P < .001). The seasonal and postseasonal increases in LTB4 and LTE4 concentrations in EBC correlated significantly with the later increase in BRM. Aim of the study was to investigate the relationship between the postseasonal increase in the concentration of leukotriene (LT) B4 and LTE4 in exhaled breath condensate (EBC) and bronchial responsiveness to methacholine (BRM) in patients with seasonal allergic rhinitis (SAR). In 28 patients with SAR and 50 healthy study patients, the leukotrienes were measured during and after the pollen season by gas chromatography/mass spectrometry. Following seasonal and postseasonal median values were measured in patients with SAR in comparison with control patients: LTB4: 131 and 90 pg/mL vs 80 and 79 pg/mL, P < .001 and P = .03, respectively; LTE4: 122 and 86 pg/mL vs 76 and 74 pg/mL, P < .001and P = .02, respectively. Five months after the pollen season, the concentrations of LTB4 and LTE4 decreased with respect to their seasonal values (P < .001). The seasonal and postseasonal increases in LTB4 and LTE4 concentrations in EBC correlated significantly with the later increase in BRM.
dcterms:title
Exhaled Leukotrienes and Bronchial Responsiveness to Methacholine in Patients with Seasonal Allergic Rhinitis Exhaled Leukotrienes and Bronchial Responsiveness to Methacholine in Patients with Seasonal Allergic Rhinitis
skos:prefLabel
Exhaled Leukotrienes and Bronchial Responsiveness to Methacholine in Patients with Seasonal Allergic Rhinitis Exhaled Leukotrienes and Bronchial Responsiveness to Methacholine in Patients with Seasonal Allergic Rhinitis
skos:notation
RIV/67985807:_____/09:00338859!RIV10-AV0-67985807
n3:aktivita
n12:Z n12:P
n3:aktivity
P(NL7024), Z(AV0Z10300504)
n3:cisloPeriodika
2
n3:dodaniDat
n14:2010
n3:domaciTvurceVysledku
n6:6064094
n3:druhVysledku
n13:J
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
314125
n3:idVysledku
RIV/67985807:_____/09:00338859
n3:jazykVysledku
n16:eng
n3:klicovaSlova
allergic rhinitis; asthma; breath condensate; leukotrienes; gas chromatography; mass spectrometry analysis
n3:klicoveSlovo
n5:mass%20spectrometry%20analysis n5:leukotrienes n5:allergic%20rhinitis n5:asthma n5:gas%20chromatography n5:breath%20condensate
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[E5848A2E03F2]
n3:nazevZdroje
Annals of Allergy Asthma & Immunology
n3:obor
n18:FN
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
4
n3:projekt
n4:NL7024
n3:rokUplatneniVysledku
n14:2009
n3:svazekPeriodika
102
n3:tvurceVysledku
Pelikán, Z. Čáp, P. Pehal, F. Malý, Marek
n3:wos
000263084000004
n3:zamer
n17:AV0Z10300504
s:issn
1081-1206
s:numberOfPages
7