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Statements

Subject Item
n2:RIV%2F65269705%3A_____%2F12%3A%230001858%21RIV13-MZ0-65269705
rdf:type
n7:Vysledek skos:Concept
dcterms:description
Aim: Determination of the importance of exercise tissue Doppler echocardiography in prognostic stratification of congestive heart failure patients with systolic dysfunction. Methods: 106 patients with congestive heart failure and LVEF 45% on optimal pharmacotherapy were included in the study. Results of resting and post-exercise echocardiography, cardiopulmonary exercise test and serum BNP levels were available for all patients. Two patient groups were constituted, based on the prognostic classification. Group I contained 21 patients with poor prognosis (defined by predicted value of pVO2 < 76% together with both VE/VCO2 slope > 32.7 and BNP > 210 pg/ml) and group II with 85 patients who did not meet the criteria. Results: The patient groups significantly differed in indexed volume of left atrium, mitral regurgitation severity, rest and post-exercise systolic velocity of mitral annulus and in rest and post-exercise E/Em. Multivariate analysis identified E/Em as the only independent predictor of prognosis. E/Em at rest (post-exercise) defined poor prognosis with sensitivity of 71% (86%) and specificity of 71% (71%). Conclusion: Our study suggests usefulness of exercise tissue Doppler echocardiography for prognostic stratification of patients with congestive heart failure with possible superiority to resting parameters. Aim: Determination of the importance of exercise tissue Doppler echocardiography in prognostic stratification of congestive heart failure patients with systolic dysfunction. Methods: 106 patients with congestive heart failure and LVEF 45% on optimal pharmacotherapy were included in the study. Results of resting and post-exercise echocardiography, cardiopulmonary exercise test and serum BNP levels were available for all patients. Two patient groups were constituted, based on the prognostic classification. Group I contained 21 patients with poor prognosis (defined by predicted value of pVO2 < 76% together with both VE/VCO2 slope > 32.7 and BNP > 210 pg/ml) and group II with 85 patients who did not meet the criteria. Results: The patient groups significantly differed in indexed volume of left atrium, mitral regurgitation severity, rest and post-exercise systolic velocity of mitral annulus and in rest and post-exercise E/Em. Multivariate analysis identified E/Em as the only independent predictor of prognosis. E/Em at rest (post-exercise) defined poor prognosis with sensitivity of 71% (86%) and specificity of 71% (71%). Conclusion: Our study suggests usefulness of exercise tissue Doppler echocardiography for prognostic stratification of patients with congestive heart failure with possible superiority to resting parameters.
dcterms:title
Usefulness of exercise tissue doppler echocardipgraphy for prognostic stratification of congestive heart failure patients with left ventricular systolic dysfunction Usefulness of exercise tissue doppler echocardipgraphy for prognostic stratification of congestive heart failure patients with left ventricular systolic dysfunction
skos:prefLabel
Usefulness of exercise tissue doppler echocardipgraphy for prognostic stratification of congestive heart failure patients with left ventricular systolic dysfunction Usefulness of exercise tissue doppler echocardipgraphy for prognostic stratification of congestive heart failure patients with left ventricular systolic dysfunction
skos:notation
RIV/65269705:_____/12:#0001858!RIV13-MZ0-65269705
n7:predkladatel
n12:ico%3A65269705
n3:aktivita
n11:I
n3:aktivity
I
n3:cisloPeriodika
10.5507/bp.2012.014
n3:dodaniDat
n5:2013
n3:domaciTvurceVysledku
n4:4766431 n4:5815894 n4:5104149 n4:9776915 n4:9215190
n3:druhVysledku
n15:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
176451
n3:idVysledku
RIV/65269705:_____/12:#0001858
n3:jazykVysledku
n9:eng
n3:klicovaSlova
heart failure
n3:klicoveSlovo
n18:heart%20failure
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[9AE74074F07F]
n3:nazevZdroje
Biomedical Papers of the Medical Faculty of Palacky University in Olomouc
n3:obor
n13:FA
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n5:2012
n3:svazekPeriodika
156
n3:tvurceVysledku
Ludka, Ondřej Galková, Lujza Musil, Viktor Špinar, Jindřich Trna, Jan
s:issn
1804-7521
s:numberOfPages
8
n6:doi
10.5507/bp.2012.014