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Statements

Subject Item
n2:RIV%2F65269705%3A_____%2F12%3A%230001660%21RIV13-MZ0-65269705
rdf:type
n14:Vysledek skos:Concept
dcterms:description
The aim of the study was to assess the dynamics of neurological soft signs (NSS) over four years from the clinical onset of schizophrenia, depending on the clinical course of the disease, and to evaluate the relationship of NSS to symptomatic dimensions in patients with first-episode schizophrenia. Sixty-eight patients with first-episode schizophrenia were included in the trial. The clinical status was assessed using Positive and Negative Syndrome Scale (PANSS) at the same time as the neurological examination, at admission to the hospital for first-episode schizophrenia and at a check-up examination four years later. The assessment of NSS using the Neurological Evaluation Scale (NES) coincided with the assessment of the clinical condition of the patients. According to the Andreasen remission criterion of schizophrenia, after four years we found that 57% of patients' were remitters and 43% were nonremitters. During the monitoring period, in remitters total NES score and sensory integration/ sequencing of motor acts items of the NES decreased. In non-remitters, increase in the total NES score and the %22others! item of the NES was observed. A connection between the dynamics of NSS and the clinical course of schizophrenia, over the period of four years, and a relationship between NSS and negative schizophrenia symptoms was found. The aim of the study was to assess the dynamics of neurological soft signs (NSS) over four years from the clinical onset of schizophrenia, depending on the clinical course of the disease, and to evaluate the relationship of NSS to symptomatic dimensions in patients with first-episode schizophrenia. Sixty-eight patients with first-episode schizophrenia were included in the trial. The clinical status was assessed using Positive and Negative Syndrome Scale (PANSS) at the same time as the neurological examination, at admission to the hospital for first-episode schizophrenia and at a check-up examination four years later. The assessment of NSS using the Neurological Evaluation Scale (NES) coincided with the assessment of the clinical condition of the patients. According to the Andreasen remission criterion of schizophrenia, after four years we found that 57% of patients' were remitters and 43% were nonremitters. During the monitoring period, in remitters total NES score and sensory integration/ sequencing of motor acts items of the NES decreased. In non-remitters, increase in the total NES score and the %22others! item of the NES was observed. A connection between the dynamics of NSS and the clinical course of schizophrenia, over the period of four years, and a relationship between NSS and negative schizophrenia symptoms was found.
dcterms:title
Dynamics of neurological soft signs and its relationship to clinical course in patients with first-episode schizophrenia Dynamics of neurological soft signs and its relationship to clinical course in patients with first-episode schizophrenia
skos:prefLabel
Dynamics of neurological soft signs and its relationship to clinical course in patients with first-episode schizophrenia Dynamics of neurological soft signs and its relationship to clinical course in patients with first-episode schizophrenia
skos:notation
RIV/65269705:_____/12:#0001660!RIV13-MZ0-65269705
n14:predkladatel
n16:ico%3A65269705
n3:aktivita
n5:P n5:Z
n3:aktivity
P(NS9890), Z(MSM0021622404)
n3:cisloPeriodika
1
n3:dodaniDat
n17:2013
n3:domaciTvurceVysledku
n6:9175474 n6:6925472 n6:7194447 n6:4520831 n6:2871386 n6:5303125 n6:3871029 n6:8381305
n3:druhVysledku
n19:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
132560
n3:idVysledku
RIV/65269705:_____/12:#0001660
n3:jazykVysledku
n11:eng
n3:klicovaSlova
schizophrenia
n3:klicoveSlovo
n13:schizophrenia
n3:kodStatuVydavatele
IE - Irsko
n3:kontrolniKodProRIV
[4BF15FF5DDD7]
n3:nazevZdroje
Psychiatry Research
n3:obor
n10:FL
n3:pocetDomacichTvurcuVysledku
8
n3:pocetTvurcuVysledku
8
n3:projekt
n8:NS9890
n3:rokUplatneniVysledku
n17:2012
n3:svazekPeriodika
200
n3:tvurceVysledku
Kašpárek, Tomáš Vrzalová, Michaela Ustohal, Libor Venclíková, Simona Češková, Eva Přikrylová Kučerová, Hana Tronerová, Silva Přikryl, Radovan
n3:wos
000313764700001
n3:zamer
n20:MSM0021622404
s:issn
0165-1781
s:numberOfPages
6
n9:doi
10.1016/j.psychres.2012.03.008