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Statements

Subject Item
n2:RIV%2F65269705%3A_____%2F11%3A%230001280%21RIV12-MZ0-65269705
rdf:type
skos:Concept n6:Vysledek
dcterms:description
Multiple myeloma (MM) is an incurable plasma cell (PC) malignancy characterized by the accumulation of monoclonal PCs in the bone marrow. For deeper understanding of the molecular mechanisms involved in the development of this disease, the influence of microenvironment, or the prediction of response of tumor PCs to anti-MM treatment, it is possible to use modern technologies for genomic and proteomic analyses. Due to progress in instrumentation, one of the main tools of proteomic analysis is mass spectrometry in combination with chosen separation techniques. This review will provide a short survey of the most commonly used proteomic techniques and show examples of their applications in MM proteome studies. Multiple myeloma (MM) is an incurable plasma cell (PC) malignancy characterized by the accumulation of monoclonal PCs in the bone marrow. For deeper understanding of the molecular mechanisms involved in the development of this disease, the influence of microenvironment, or the prediction of response of tumor PCs to anti-MM treatment, it is possible to use modern technologies for genomic and proteomic analyses. Due to progress in instrumentation, one of the main tools of proteomic analysis is mass spectrometry in combination with chosen separation techniques. This review will provide a short survey of the most commonly used proteomic techniques and show examples of their applications in MM proteome studies.
dcterms:title
Proteomic analysis in multiple myeloma research Proteomic analysis in multiple myeloma research
skos:prefLabel
Proteomic analysis in multiple myeloma research Proteomic analysis in multiple myeloma research
skos:notation
RIV/65269705:_____/11:#0001280!RIV12-MZ0-65269705
n6:predkladatel
n7:ico%3A65269705
n3:aktivita
n8:P n8:Z
n3:aktivity
P(LC06027), P(NS9683), Z(MSM0021622415), Z(MSM0021622434)
n3:cisloPeriodika
1
n3:dodaniDat
n18:2012
n3:domaciTvurceVysledku
n4:9622748
n3:druhVysledku
n10:J
n3:duvernostUdaju
n20:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
224825
n3:idVysledku
RIV/65269705:_____/11:#0001280
n3:jazykVysledku
n13:eng
n3:klicovaSlova
multiple myeloma
n3:klicoveSlovo
n16:multiple%20myeloma
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[5CFACD1444E4]
n3:nazevZdroje
Molecular Biotechnology
n3:obor
n12:FD
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
4
n3:projekt
n11:LC06027 n11:NS9683
n3:rokUplatneniVysledku
n18:2011
n3:svazekPeriodika
47
n3:tvurceVysledku
Hájek, Roman Čumová, Jana
n3:wos
000285472500010
n3:zamer
n19:MSM0021622415 n19:MSM0021622434
s:issn
1073-6085
s:numberOfPages
11
n15:doi
10.1007/s12033-010-9326-x