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Statements

Subject Item
n2:RIV%2F62690094%3A18470%2F12%3A50002978%21RIV15-MSM-18470___
rdf:type
skos:Concept n17:Vysledek
rdfs:seeAlso
http://informahealthcare.com/doi/abs/10.3109/1354750X.2012.692392
dcterms:description
Among ochratoxins, ochratoxin A (OTA) occupies a dominant place and represents significant risk for human and animal health which also implies economic losses around the world. OTA is nephrotoxic, hepatotoxic, teratogenic and immunotoxic mycotoxin. OTA exposure may lead to formation of DNA adducts resulting to genotoxicity and carcinogenicity (human carcinogen of 2B group). Now it seems that OTA could be “a complete carcinogen” which obliges to monitor its presence in biological materials, especially using the suitable biomarkers. In this article, OTA findings in urine, blood, serum, plasma and human kidneys (target dose) in the Czech Republic and comparison with foreign countries are presented. Among ochratoxins, ochratoxin A (OTA) occupies a dominant place and represents significant risk for human and animal health which also implies economic losses around the world. OTA is nephrotoxic, hepatotoxic, teratogenic and immunotoxic mycotoxin. OTA exposure may lead to formation of DNA adducts resulting to genotoxicity and carcinogenicity (human carcinogen of 2B group). Now it seems that OTA could be “a complete carcinogen” which obliges to monitor its presence in biological materials, especially using the suitable biomarkers. In this article, OTA findings in urine, blood, serum, plasma and human kidneys (target dose) in the Czech Republic and comparison with foreign countries are presented.
dcterms:title
Ochratoxin A exposure biomarkers in the Czech Republic and comparison with foreign countries Ochratoxin A exposure biomarkers in the Czech Republic and comparison with foreign countries
skos:prefLabel
Ochratoxin A exposure biomarkers in the Czech Republic and comparison with foreign countries Ochratoxin A exposure biomarkers in the Czech Republic and comparison with foreign countries
skos:notation
RIV/62690094:18470/12:50002978!RIV15-MSM-18470___
n3:aktivita
n8:I
n3:aktivity
I
n3:cisloPeriodika
7
n3:dodaniDat
n4:2015
n3:domaciTvurceVysledku
n11:8812853
n3:druhVysledku
n5:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
155733
n3:idVysledku
RIV/62690094:18470/12:50002978
n3:jazykVysledku
n13:eng
n3:klicovaSlova
biomarkers; exposure; OTA; ochratoxin A; Monitoring
n3:klicoveSlovo
n14:Monitoring n14:exposure n14:biomarkers n14:ochratoxin%20A n14:OTA
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[39708EE44F78]
n3:nazevZdroje
Biomarkers
n3:obor
n10:FP
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n4:2012
n3:svazekPeriodika
17
n3:tvurceVysledku
Ostrý, Vladimír Pfohl-Leszkowicz, Annie Malíř, František Roubal, Tomáš
n3:wos
000310077200001
s:issn
1354-750X
s:numberOfPages
13
n19:doi
10.3109/1354750X.2012.692392
n12:organizacniJednotka
18470