This HTML5 document contains 49 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n11http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F62157124%3A16370%2F09%3A00002090%21RIV10-MSM-16370___/
dctermshttp://purl.org/dc/terms/
n15http://localhost/temp/predkladatel/
n4http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n17http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n5http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n16http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n13http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n14http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n7http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n12http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F62157124%3A16370%2F09%3A00002090%21RIV10-MSM-16370___
rdf:type
skos:Concept n17:Vysledek
dcterms:description
We have investigated anticholinesterase potential of the methanol extracts from the leaf, wood, flower, twig, and stem bark of the female and male individuals and rhizodermis and fruit from the female tree of Maclura pomifera (Rafin.) Schneider (Moraceae) along with its major isoflavonoids; osajin and pomiferin as well as their semi-synthetic derivatives; iso-osajin and iso-pomiferin. Anticholinesterase activity was determined by Ellman method using ELISA microplate reader. Osajin and pomiferin had a noticeable inhibition of AChE with IC(50) values of 2.239 and 0.096 mM, respectively, while their iso-derivatives were found to display less inhibition towards AChE. The extracts and compounds did not inhibit BChE. The extracts were analyzed for osajin and pomiferin contents by LC-DAD-MS and only the fruits and female flowers contained osajin (fruit: 8.87%, female flowers: 0.19%, w/w) and pomiferin (fruit: 13.6%, female flowers: 0.36%, w/w). We have investigated anticholinesterase potential of the methanol extracts from the leaf, wood, flower, twig, and stem bark of the female and male individuals and rhizodermis and fruit from the female tree of Maclura pomifera (Rafin.) Schneider (Moraceae) along with its major isoflavonoids; osajin and pomiferin as well as their semi-synthetic derivatives; iso-osajin and iso-pomiferin. Anticholinesterase activity was determined by Ellman method using ELISA microplate reader. Osajin and pomiferin had a noticeable inhibition of AChE with IC(50) values of 2.239 and 0.096 mM, respectively, while their iso-derivatives were found to display less inhibition towards AChE. The extracts and compounds did not inhibit BChE. The extracts were analyzed for osajin and pomiferin contents by LC-DAD-MS and only the fruits and female flowers contained osajin (fruit: 8.87%, female flowers: 0.19%, w/w) and pomiferin (fruit: 13.6%, female flowers: 0.36%, w/w).
dcterms:title
Cholinesterase inhibitory effects of the extracts and compounds of Maclura pomifera (Rafin.) Schneider Cholinesterase inhibitory effects of the extracts and compounds of Maclura pomifera (Rafin.) Schneider
skos:prefLabel
Cholinesterase inhibitory effects of the extracts and compounds of Maclura pomifera (Rafin.) Schneider Cholinesterase inhibitory effects of the extracts and compounds of Maclura pomifera (Rafin.) Schneider
skos:notation
RIV/62157124:16370/09:00002090!RIV10-MSM-16370___
n3:aktivita
n13:S
n3:aktivity
S
n3:cisloPeriodika
8
n3:dodaniDat
n12:2010
n3:domaciTvurceVysledku
n4:1363603 n4:7985479 n4:4091647 n4:6931715
n3:druhVysledku
n14:J
n3:duvernostUdaju
n16:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
306994
n3:idVysledku
RIV/62157124:16370/09:00002090
n3:jazykVysledku
n9:eng
n3:klicovaSlova
Maclura pomifera (Rafin.) Schneider; Osage orange; Moraceae; Anticholinesterase; Isoflavone; LC?DAD?MS
n3:klicoveSlovo
n5:Isoflavone n5:Osage%20orange n5:Maclura%20pomifera%20%28Rafin.%29%20Schneider n5:Anticholinesterase n5:Moraceae n5:LC%3FDAD%3FMS
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[F05C2C85A3CA]
n3:nazevZdroje
Food and Chemical Toxicology
n3:obor
n7:FR
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
7
n3:rokUplatneniVysledku
n12:2009
n3:svazekPeriodika
47
n3:tvurceVysledku
Mokrý, Petr Dvorská, Margita Senol, Sezer Orhan, Ilkay Šmejkal, Karel Kartal, Murat Žemlička, Milan
n3:wos
000269100700004
s:issn
0278-6915
s:numberOfPages
5
n15:organizacniJednotka
16370