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Statements

Subject Item
n2:RIV%2F62157124%3A16370%2F02%3A00000657%21RIV%2F2003%2FMSM%2F163703%2FN
rdf:type
n12:Vysledek skos:Concept
dcterms:description
The influence of the newly developed ultrashort acting beta-adrenergic blockers on the heart rate was measured on laboratory male Wistar rats with normal blood pressure. Three tested compounds were injected intravenously under general anaesthesia into the animals. At specific time intervals, the heart rate in all animals was measured from a record of their ECG. These results were converted into the percentages of perturbations of the heart rate. All evaluated compounds have shown a significant verifiable short-term bradycardic effect on the heart rate. The most significant reduction was observed in the first few minutes after i.v. administration. The influence of the newly developed ultrashort acting beta-adrenergic blockers on the heart rate was measured on laboratory male Wistar rats with normal blood pressure. Three tested compounds were injected intravenously under general anaesthesia into the animals. At specific time intervals, the heart rate in all animals was measured from a record of their ECG. These results were converted into the percentages of perturbations of the heart rate. All evaluated compounds have shown a significant verifiable short-term bradycardic effect on the heart rate. The most significant reduction was observed in the first few minutes after i.v. administration.
dcterms:title
Observation of changes in heart rate after newly developed ultrashort acting beta-adrenergic blockers were applied Observation of changes in heart rate after newly developed ultrashort acting beta-adrenergic blockers were applied
skos:prefLabel
Observation of changes in heart rate after newly developed ultrashort acting beta-adrenergic blockers were applied Observation of changes in heart rate after newly developed ultrashort acting beta-adrenergic blockers were applied
skos:notation
RIV/62157124:16370/02:00000657!RIV/2003/MSM/163703/N
n3:strany
303-304
n3:aktivita
n13:Z
n3:aktivity
Z(MSM 163700003)
n3:cisloPeriodika
9
n3:dodaniDat
n10:2003
n3:domaciTvurceVysledku
n6:9818545 n6:9312579 n6:7985479 n6:4796071 n6:6316794
n3:druhVysledku
n17:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
656492
n3:idVysledku
RIV/62157124:16370/02:00000657
n3:jazykVysledku
n4:eng
n3:klicovaSlova
Ultrashort acting beta-blockers, heart rate, ECG changes, ion channels
n3:klicoveSlovo
n5:ion%20channels n5:heart%20rate n5:Ultrashort%20acting%20beta-blockers n5:ECG%20changes
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[E372481256AD]
n3:nazevZdroje
Bratislavske Lekarske Listy
n3:obor
n18:FR
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
7
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:rokUplatneniVysledku
n10:2002
n3:svazekPeriodika
103
n3:tvurceVysledku
Bartošíková, Lenka Florian, Tomáš Mokrý, Petr Frydrych, Marek Bartošová, Ladislava Brunclík, Vít Nečas, Jiří
n3:zamer
n9:MSM%20163700003
s:issn
0006-9248
s:numberOfPages
1
n14:organizacniJednotka
16370