This HTML5 document contains 51 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n19http://localhost/temp/predkladatel/
n20http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n14http://linked.opendata.cz/resource/domain/vavai/projekt/
n11http://linked.opendata.cz/resource/domain/vavai/subjekt/
n10http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
rdfshttp://www.w3.org/2000/01/rdf-schema#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n5http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n9http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F62157124%3A16270%2F12%3A43871396%21RIV13-MSM-16270___/
n6http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n12http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n18http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n8http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n21http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n7http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F62157124%3A16270%2F12%3A43871396%21RIV13-MSM-16270___
rdf:type
skos:Concept n10:Vysledek
rdfs:seeAlso
http://web2.mendelu.cz/af_239_nanotech/data/pub/138-12_Sobrova_author.pdf
dcterms:description
Deoxynivalenol (DON, vomitoxin) is one of several human mycotoxins acquired through residues in foods of plant origin (cereals) and through foods of animal origin (kidneys, liver, milk, eggs). The aim of this study was to investigate the impact of deoxynivalenol-contaminated mouldy grain on the health status of rats and their ability to resist oxidative stress. The rats were fed a diet supplemented with DON along with organic and inorganic Zn(II), and vitamins for 28 days. The study focuses particularly on protective mechanisms and levels of reduced glutathione and metallothioneins (MT) against the adverse effects of xenobiotics. The highest concentrations of MT were detected in the tissues of kidneys ((6.70 +- 0.05) mýg g?1) and liver ((6.00 +- 0.05) mýg g?1), both of which are involved in detoxifying cationic xenobiotics. Lower concentrations were also detected in heart, brain, testes, and muscle tissues (approximately 3.0 mýg g?1). Antioxidant capacity, glutathione-S-transferase, and liver enzymes activity were also studied. In conclusion, MT may play an important role in the detoxification of mycotoxins. Even though its role is not fully understood, MT are crucial for the redistribution of ions important for transcription factors and interaction with reactive oxygen species that form mycotoxins. Deoxynivalenol (DON, vomitoxin) is one of several human mycotoxins acquired through residues in foods of plant origin (cereals) and through foods of animal origin (kidneys, liver, milk, eggs). The aim of this study was to investigate the impact of deoxynivalenol-contaminated mouldy grain on the health status of rats and their ability to resist oxidative stress. The rats were fed a diet supplemented with DON along with organic and inorganic Zn(II), and vitamins for 28 days. The study focuses particularly on protective mechanisms and levels of reduced glutathione and metallothioneins (MT) against the adverse effects of xenobiotics. The highest concentrations of MT were detected in the tissues of kidneys ((6.70 +- 0.05) mýg g?1) and liver ((6.00 +- 0.05) mýg g?1), both of which are involved in detoxifying cationic xenobiotics. Lower concentrations were also detected in heart, brain, testes, and muscle tissues (approximately 3.0 mýg g?1). Antioxidant capacity, glutathione-S-transferase, and liver enzymes activity were also studied. In conclusion, MT may play an important role in the detoxification of mycotoxins. Even though its role is not fully understood, MT are crucial for the redistribution of ions important for transcription factors and interaction with reactive oxygen species that form mycotoxins.
dcterms:title
Study of deoxynivalenol effect on metallothionein and glutathione levels, antioxidant capacity, and glutathione-S-transferase and liver enzymes activity in rats Study of deoxynivalenol effect on metallothionein and glutathione levels, antioxidant capacity, and glutathione-S-transferase and liver enzymes activity in rats
skos:prefLabel
Study of deoxynivalenol effect on metallothionein and glutathione levels, antioxidant capacity, and glutathione-S-transferase and liver enzymes activity in rats Study of deoxynivalenol effect on metallothionein and glutathione levels, antioxidant capacity, and glutathione-S-transferase and liver enzymes activity in rats
skos:notation
RIV/62157124:16270/12:43871396!RIV13-MSM-16270___
n10:predkladatel
n11:orjk%3A16270
n3:aktivita
n8:P n8:V
n3:aktivity
P(ED1.1.00/02.0068), P(KAN208130801), V
n3:cisloPeriodika
12
n3:dodaniDat
n7:2013
n3:domaciTvurceVysledku
n20:4771079
n3:druhVysledku
n21:J
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n9:predkladatel
n3:idSjednocenehoVysledku
172144
n3:idVysledku
RIV/62157124:16270/12:43871396
n3:jazykVysledku
n18:eng
n3:klicovaSlova
metallothionein; deoxynivalenol; mycotoxins; mouldy barley; rats
n3:klicoveSlovo
n6:metallothionein n6:rats n6:mouldy%20barley n6:mycotoxins n6:deoxynivalenol
n3:kodStatuVydavatele
SK - Slovenská republika
n3:kontrolniKodProRIV
[107D069A6364]
n3:nazevZdroje
Chemical Papers - Chemické Zvesti
n3:obor
n13:CE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
7
n3:projekt
n14:KAN208130801 n14:ED1.1.00%2F02.0068
n3:rokUplatneniVysledku
n7:2012
n3:svazekPeriodika
66
n3:tvurceVysledku
Šobrová, Pavlína Kizek, René Vašátková, Anna Adam, Vojtěch Beklová, Miroslava Skládanka, Jiří Zeman, Ladislav
n3:wos
000308649300002
s:issn
0366-6352
s:numberOfPages
11
n5:doi
10.2478/s11696-012-0229-0
n19:organizacniJednotka
16270