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Statements

Subject Item
n2:RIV%2F62157124%3A16170%2F09%3A00002516%21RIV10-MZ0-16170___
rdf:type
n5:Vysledek skos:Concept
dcterms:description
Background/Aims: Recent studies demonstrated that extra vascular lung water (EVLW) is a reliable and independent marker for outcome. The primary therapeutically goal in critically ill patients is to resuscitate and retain adequate organ perfusion by fluid administration, where is necessary to achieve adequate intravascular filling, but avoid initiation of pulmonary edema. Methodology: Patients with severe sepsis randomly allocated to a group treated with 20% albumin 100 ml every 12 hours (ALB; n=30) or with 6% hydroxyethylstarch 130/0,4 250 ml every 6 hours (HES; n=26). Both treatments were completed by crystalloids or norephinephrin as necessary. We analyzed amount of developed EVLW, and relation with mortality, PaO2/FiO2 and alveolo-arterial oxygen difference. Results: We observed significantly greater decrease of EVLW when compared with baseline during whole monitored period of 72 hours in ALB group in contrast to HES patients (P<0.05). Despite no significant changes of EVLW in HES group, we not Background/Aims: Recent studies demonstrated that extra vascular lung water (EVLW) is a reliable and independent marker for outcome. The primary therapeutically goal in critically ill patients is to resuscitate and retain adequate organ perfusion by fluid administration, where is necessary to achieve adequate intravascular filling, but avoid initiation of pulmonary edema. Methodology: Patients with severe sepsis randomly allocated to a group treated with 20% albumin 100 ml every 12 hours (ALB; n=30) or with 6% hydroxyethylstarch 130/0,4 250 ml every 6 hours (HES; n=26). Both treatments were completed by crystalloids or norephinephrin as necessary. We analyzed amount of developed EVLW, and relation with mortality, PaO2/FiO2 and alveolo-arterial oxygen difference. Results: We observed significantly greater decrease of EVLW when compared with baseline during whole monitored period of 72 hours in ALB group in contrast to HES patients (P<0.05). Despite no significant changes of EVLW in HES group, we not
dcterms:title
Thearapeutic influence of 20% albumin versus 6% hydroxyethylstarch on extravascular lung water in septic patiens: A randomised controlled trail. Thearapeutic influence of 20% albumin versus 6% hydroxyethylstarch on extravascular lung water in septic patiens: A randomised controlled trail.
skos:prefLabel
Thearapeutic influence of 20% albumin versus 6% hydroxyethylstarch on extravascular lung water in septic patiens: A randomised controlled trail. Thearapeutic influence of 20% albumin versus 6% hydroxyethylstarch on extravascular lung water in septic patiens: A randomised controlled trail.
skos:notation
RIV/62157124:16170/09:00002516!RIV10-MZ0-16170___
n3:aktivita
n11:P
n3:aktivity
P(NR8561)
n3:cisloPeriodika
6
n3:dodaniDat
n4:2010
n3:domaciTvurceVysledku
n15:1031279
n3:druhVysledku
n9:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
346142
n3:idVysledku
RIV/62157124:16170/09:00002516
n3:jazykVysledku
n10:eng
n3:klicovaSlova
hydroxyethylstarch; pulmonary edema; severe sepsis
n3:klicoveSlovo
n6:pulmonary%20edema n6:hydroxyethylstarch n6:severe%20sepsis
n3:kodStatuVydavatele
GR - Řecká republika
n3:kontrolniKodProRIV
[001B6D28984D]
n3:nazevZdroje
Hepato-Gastroenterology
n3:obor
n7:FE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
8
n3:projekt
n13:NR8561
n3:rokUplatneniVysledku
n4:2009
n3:svazekPeriodika
56
n3:tvurceVysledku
Doleček, Martin Sas, Igor Radvan, Martin Scheer, Peter Radvanová, Jana Kantorová, Ilona Svoboda, Petr Bíbrová, Jitka
n3:wos
000273294100008
s:issn
0172-6390
s:numberOfPages
5
n18:organizacniJednotka
16170