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Statements

Subject Item
n2:RIV%2F62157124%3A16170%2F08%3A00001940%21RIV09-MZ0-16170___
rdf:type
skos:Concept n13:Vysledek
dcterms:description
This study was concerned with the development of induced septic shock in a laboratory rat using a series of measurements including body temperature, heart and respiratory rates, haematocrit value, red and white blood cell counts, differential leukocyte count, haemoglobin value, glycaemia, analysis of arterial blood gases, and serum levels of interleukin 6 (IL-6) during the first five hours. A total of 12 specific pathogen free (SPF) laboratory rats were used for the study. Septic shock was induced under general anaesthesia by introducing live E. coli (O18) into the jugular vein in the dose of 1 x 109 per 100 g of body weight (group SESH). Clinical measurements and blood collection from a. carotis were performed just prior to, and then 1.5 and 5 h after the administration of E. coli. The control group (C) contained 9 SPF laboratory rats which received physiological saline only, at the same volume into the jugular vein, and blood collection followed according to the same scheme as above described for gr Práce byla zaměřena na vývoj modelu indukovaného septického šoku u laboratorního potkana za použití série měření zahrnujících tělesnou teplotu, dechovou a tepovou frekvenci, hematokrit, počty červených a bílých krvinek, diferenciální rozpočet leukocytů, koncentraci hemoglobinu, glykémii, analýzu arteriálních krevních plynů a hodoty interleukinu 6 (IĹ-6) v průběhu prvních pěti hodin. This study was concerned with the development of induced septic shock in a laboratory rat using a series of measurements including body temperature, heart and respiratory rates, haematocrit value, red and white blood cell counts, differential leukocyte count, haemoglobin value, glycaemia, analysis of arterial blood gases, and serum levels of interleukin 6 (IL-6) during the first five hours. A total of 12 specific pathogen free (SPF) laboratory rats were used for the study. Septic shock was induced under general anaesthesia by introducing live E. coli (O18) into the jugular vein in the dose of 1 x 109 per 100 g of body weight (group SESH). Clinical measurements and blood collection from a. carotis were performed just prior to, and then 1.5 and 5 h after the administration of E. coli. The control group (C) contained 9 SPF laboratory rats which received physiological saline only, at the same volume into the jugular vein, and blood collection followed according to the same scheme as above described for gr
dcterms:title
Model of septic shock induced by live E-coli (O18) in a laboratory rat Model septického šoku u laboratorního potkana indukovaného živou E-coli (O18) Model of septic shock induced by live E-coli (O18) in a laboratory rat
skos:prefLabel
Model of septic shock induced by live E-coli (O18) in a laboratory rat Model septického šoku u laboratorního potkana indukovaného živou E-coli (O18) Model of septic shock induced by live E-coli (O18) in a laboratory rat
skos:notation
RIV/62157124:16170/08:00001940!RIV09-MZ0-16170___
n4:aktivita
n12:P
n4:aktivity
P(NR9284)
n4:cisloPeriodika
3
n4:dodaniDat
n8:2009
n4:domaciTvurceVysledku
n14:1031279 n14:5940362 n14:5997933 n14:9388583
n4:druhVysledku
n11:J
n4:duvernostUdaju
n7:S
n4:entitaPredkladatele
n5:predkladatel
n4:idSjednocenehoVysledku
379822
n4:idVysledku
RIV/62157124:16170/08:00001940
n4:jazykVysledku
n17:eng
n4:klicovaSlova
INTERLEUKIN-6; MORTALITY; DOGS; ENDOTOXEMIA; DYSFUNCTION
n4:klicoveSlovo
n6:DYSFUNCTION n6:INTERLEUKIN-6 n6:MORTALITY n6:DOGS n6:ENDOTOXEMIA
n4:kodStatuVydavatele
CZ - Česká republika
n4:kontrolniKodProRIV
[2E846C456B1A]
n4:nazevZdroje
Veterinární medicína
n4:obor
n10:FE
n4:pocetDomacichTvurcuVysledku
4
n4:pocetTvurcuVysledku
7
n4:projekt
n18:NR9284
n4:rokUplatneniVysledku
n8:2008
n4:svazekPeriodika
53
n4:tvurceVysledku
Řeháková, Kristina Tomenendálová, Jaroslava Dembovská, Kateřina Svoboda, Petr Doubek, Jaroslav Scheer, Peter Kantorová, Ilona
n4:wos
000254745400004
s:issn
0375-8427
s:numberOfPages
11
n16:organizacniJednotka
16170