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Statements

Subject Item
n2:RIV%2F62156489%3A_____%2F01%3A23100005%21RIV%2F2002%2FMSM%2F430002%2FN
rdf:type
skos:Concept n13:Vysledek
dcterms:description
The role of neutrophil apoptosis in the resolution of bovine mammary gland injury induced by intramammary administration of physiological buffered saline (PBS) or lipopolysaccharide (LPS) was investigated. 1Wenty mammary glands of five non-pregnant heifers were used in the two studies and each animal received both stimuli. Samples of cell populations were collected by mammary gland lavages before and 24, 48, 72 and 96 hours after treatment and examined by light microscopy and staining for myeloperoxidase (MPQ). A marked influx of neutrophils into the mammary gland was observed 24 hours after stimulation. At the same time, apoptotic neutrophils and MPO-positive macrophages (MAC) were identified in the samples. The numbers increased to reach maximum values at 48 hours after stimulation with PBS and at 72 hours after stimulation with LPS. The observed differences in the length of the resolution period indicate that neutrophil viability can be modulated by delaying the apoptotic process. The role of neutrophil apoptosis in the resolution of bovine mammary gland injury induced by intramammary administration of physiological buffered saline (PBS) or lipopolysaccharide (LPS) was investigated. 1Wenty mammary glands of five non-pregnant heifers were used in the two studies and each animal received both stimuli. Samples of cell populations were collected by mammary gland lavages before and 24, 48, 72 and 96 hours after treatment and examined by light microscopy and staining for myeloperoxidase (MPQ). A marked influx of neutrophils into the mammary gland was observed 24 hours after stimulation. At the same time, apoptotic neutrophils and MPO-positive macrophages (MAC) were identified in the samples. The numbers increased to reach maximum values at 48 hours after stimulation with PBS and at 72 hours after stimulation with LPS. The observed differences in the length of the resolution period indicate that neutrophil viability can be modulated by delaying the apoptotic process.
dcterms:title
Neutrophil apoptosis during the resolution of bovine mammary gland injury Neutrophil apoptosis during the resolution of bovine mammary gland injury
skos:prefLabel
Neutrophil apoptosis during the resolution of bovine mammary gland injury Neutrophil apoptosis during the resolution of bovine mammary gland injury
skos:notation
RIV/62156489:_____/01:23100005!RIV/2002/MSM/430002/N
n3:strany
41;46
n3:aktivita
n16:Z
n3:aktivity
Z(MSM 432100001), Z(MZE-M03-99-01)
n3:cisloPeriodika
Februar
n3:dodaniDat
n12:2002
n3:domaciTvurceVysledku
n7:9869522
n3:druhVysledku
n8:J
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
688692
n3:idVysledku
RIV/62156489:_____/01:23100005
n3:jazykVysledku
n6:eng
n3:klicovaSlova
apoptosis; bovine mammary gland
n3:klicoveSlovo
n9:apoptosis n9:bovine%20mammary%20gland
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[2616378846DC]
n3:nazevZdroje
Research in Veterinary Science
n3:obor
n17:GG
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
2
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:rokUplatneniVysledku
n12:2001
n3:svazekPeriodika
70
n3:tvurceVysledku
Sládek, Zbyšek
n3:zamer
n11:MSM%20432100001 n11:MZE-M03-99-01
s:issn
0034-5228
s:numberOfPages
6