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Statements

Subject Item
n2:RIV%2F62156489%3A43210%2F12%3A00198837%21RIV13-GA0-43210___
rdf:type
skos:Concept n16:Vysledek
dcterms:description
Current development of miniature analytical instruments for detecting heavy metals in various samples is very dynamic. The most interesting representatives of these instruments are biosensors, which combine the physico-chemical transducer with biological components. Biosensors operate on different principles and their preparation can lead to the acquisition of tools with high sensitivity and selectivity against individual heavy metal ions or their mixtures. In this paper, various types of biosensors divided according to their biological components for the detection of heavy metals ions are discussed. Generally, biosensors for heavy metals detection can be divided into two groups, based on their biological part: i) protein biosensors and ii) biosensors based on nucleic acids. Biosensors using nucleic acids represent new and quickly developing branch. Protein biosensors can be divided into enzymatic and affinity ones, while enzymatic biosensors are based on activation or inhibition enzymes activity the affinity biosensors use specific antibodies. Affinity biosensors using immunodetection belong to other method for metal ion determination, which - in comparing with traditional detection methods - brings certain advantages, such as high sensitivity and selectivity. They are theoretically useful for other metal complexes, where the antibody can be prepared. Biosensors belong to the most powerful bioanalytical tools and represent future in development of instruments which can be used in medicine and pharmaceutical research, environment and BioDefence techniques and in monitoring of food quality and safety. Current development of miniature analytical instruments for detecting heavy metals in various samples is very dynamic. The most interesting representatives of these instruments are biosensors, which combine the physico-chemical transducer with biological components. Biosensors operate on different principles and their preparation can lead to the acquisition of tools with high sensitivity and selectivity against individual heavy metal ions or their mixtures. In this paper, various types of biosensors divided according to their biological components for the detection of heavy metals ions are discussed. Generally, biosensors for heavy metals detection can be divided into two groups, based on their biological part: i) protein biosensors and ii) biosensors based on nucleic acids. Biosensors using nucleic acids represent new and quickly developing branch. Protein biosensors can be divided into enzymatic and affinity ones, while enzymatic biosensors are based on activation or inhibition enzymes activity the affinity biosensors use specific antibodies. Affinity biosensors using immunodetection belong to other method for metal ion determination, which - in comparing with traditional detection methods - brings certain advantages, such as high sensitivity and selectivity. They are theoretically useful for other metal complexes, where the antibody can be prepared. Biosensors belong to the most powerful bioanalytical tools and represent future in development of instruments which can be used in medicine and pharmaceutical research, environment and BioDefence techniques and in monitoring of food quality and safety.
dcterms:title
Biosensors for detection of heavy metals Biosensors for detection of heavy metals
skos:prefLabel
Biosensors for detection of heavy metals Biosensors for detection of heavy metals
skos:notation
RIV/62156489:43210/12:00198837!RIV13-GA0-43210___
n16:predkladatel
n17:orjk%3A43210
n3:aktivita
n10:P
n3:aktivity
P(GA102/08/1546), P(KAN208130801)
n3:dodaniDat
n13:2013
n3:domaciTvurceVysledku
n6:4995775 n6:4489705 n6:7333323 n6:3790185 n6:2307049
n3:druhVysledku
n20:C
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
125184
n3:idVysledku
RIV/62156489:43210/12:00198837
n3:jazykVysledku
n5:eng
n3:klicovaSlova
biosensors; detection; heavy metals
n3:klicoveSlovo
n8:biosensors n8:heavy%20metals n8:detection
n3:kontrolniKodProRIV
[5C0BA42327CE]
n3:mistoVydani
London, UK
n3:nazevEdiceCisloSvazku
1
n3:nazevZdroje
Biosensors and Environmental Health
n3:obor
n4:CB
n3:pocetDomacichTvurcuVysledku
5
n3:pocetStranKnihy
350
n3:pocetTvurcuVysledku
5
n3:projekt
n9:GA102%2F08%2F1546 n9:KAN208130801
n3:rokUplatneniVysledku
n13:2012
n3:tvurceVysledku
Trnková, Libuše Hubálek, Jaromír Adam, Vojtěch Kizek, René Šobrová, Pavlína
s:numberOfPages
13
n15:hasPublisher
CRC Press
n12:isbn
978-1-57808-735-8
n21:organizacniJednotka
43210