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Statements

Subject Item
n2:RIV%2F62156489%3A43210%2F12%3A00192216%21RIV13-TA0-43210___
rdf:type
skos:Concept n13:Vysledek
dcterms:description
The aim of this study is to demonstrate antimicrobial activity of selected positively charged water-soluble phthalocyanines. 12 phthalocyanine derivatives were used for this study. All the tested compounds were synthesized in Centre of Organic Chemistry (COC, Rybitví, Czech republic). Water soluble phthalocyanine derivatives were prepared by peripherally substitution of the phthalocyanine skeleton with the aim to prepare cationic phthalocyanines with an ability to have a wide-spectrum antimicrobial effect. To determine the antimicrobial effects of phthalocyanines, bacterial strains Escherichia coli CCM 3988, Enterococcus faecalis CCM 4224, and Pseudomonas aeruginosa CCM 1960 were used. Phthalocyanine samples were tested in two concentrations - 0.1 and 0.5 g/l. In a sterile vial, phthalocyanine solution with the bacteria was shaken under artificial light at room temperature. The suspension was sampled at 1st, 2nd and 3rd hour. Samples were subsequently inoculated on Petri dishes with nutrient medium. The control sample was prepared by the same procedure. After the cultivation of Petri dishes, accrued colonies were counted and the results were expressed in CFU/ml. Antimicrobial action of phthalocyanines has been demonstrated. The aim of this study is to demonstrate antimicrobial activity of selected positively charged water-soluble phthalocyanines. 12 phthalocyanine derivatives were used for this study. All the tested compounds were synthesized in Centre of Organic Chemistry (COC, Rybitví, Czech republic). Water soluble phthalocyanine derivatives were prepared by peripherally substitution of the phthalocyanine skeleton with the aim to prepare cationic phthalocyanines with an ability to have a wide-spectrum antimicrobial effect. To determine the antimicrobial effects of phthalocyanines, bacterial strains Escherichia coli CCM 3988, Enterococcus faecalis CCM 4224, and Pseudomonas aeruginosa CCM 1960 were used. Phthalocyanine samples were tested in two concentrations - 0.1 and 0.5 g/l. In a sterile vial, phthalocyanine solution with the bacteria was shaken under artificial light at room temperature. The suspension was sampled at 1st, 2nd and 3rd hour. Samples were subsequently inoculated on Petri dishes with nutrient medium. The control sample was prepared by the same procedure. After the cultivation of Petri dishes, accrued colonies were counted and the results were expressed in CFU/ml. Antimicrobial action of phthalocyanines has been demonstrated.
dcterms:title
Test of phthalocyanines antimicrobial activity Test of phthalocyanines antimicrobial activity
skos:prefLabel
Test of phthalocyanines antimicrobial activity Test of phthalocyanines antimicrobial activity
skos:notation
RIV/62156489:43210/12:00192216!RIV13-TA0-43210___
n13:predkladatel
n21:orjk%3A43210
n3:aktivita
n7:P
n3:aktivity
P(TA01010356)
n3:dodaniDat
n12:2013
n3:domaciTvurceVysledku
n8:2001209 n8:6831214 n8:1545515
n3:druhVysledku
n20:D
n3:duvernostUdaju
n11:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
173987
n3:idVysledku
RIV/62156489:43210/12:00192216
n3:jazykVysledku
n18:eng
n3:klicovaSlova
microorganisms; antimicrobial activity; phtalocyanines
n3:klicoveSlovo
n9:antimicrobial%20activity n9:phtalocyanines n9:microorganisms
n3:kontrolniKodProRIV
[ACD20151FE06]
n3:mistoKonaniAkce
Brno, 23.- 25. 10. 2012
n3:mistoVydani
Ostrava, Czech Republic, EU
n3:nazevZdroje
NANOCON 2012
n3:obor
n10:EE
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
7
n3:projekt
n14:TA01010356
n3:rokUplatneniVysledku
n12:2012
n3:tvurceVysledku
Konečná, Marie Kořínková, Radka Kalhotka, Libor Přichystalová, Jitka Kubáč, Lubomír Lev, Jaroslav Hrdinová, Zuzana
n3:typAkce
n17:WRD
n3:zahajeniAkce
2012-01-01+01:00
s:numberOfPages
6
n22:hasPublisher
TANGER Ltd.
n19:isbn
978-80-87294-32-1
n5:organizacniJednotka
43210