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Statements

Subject Item
n2:RIV%2F62156489%3A43210%2F11%3A00181077%21RIV14-MSM-43210___
rdf:type
n7:Vysledek skos:Concept
dcterms:description
The major histocompatibility complex (MHC) genes coding for antigen presenting molecules are the most polymorphic genes in vertebrate genome. The MHC class II DRA gene shows only small variation in many mammalian species, but it exhibits relatively high level of polymorphism in Equidae, especially in donkeys. This extraordinary degree of polymorphism together with signatures of selection in specific amino acids sites makes the donkey DRA gene a suitable model for population diversity studies. The objective of this study was to investigate the DRA gene diversity in three different populations of donkeys under infectious pressure of protozoan parasites, Theileria equi and Babesia caballi. Three populations of domestic donkeys from Italy (N = 68), Jordan (N = 43), and Kenya (N = 78) were studied. The major histocompatibility complex (MHC) genes coding for antigen presenting molecules are the most polymorphic genes in vertebrate genome. The MHC class II DRA gene shows only small variation in many mammalian species, but it exhibits relatively high level of polymorphism in Equidae, especially in donkeys. This extraordinary degree of polymorphism together with signatures of selection in specific amino acids sites makes the donkey DRA gene a suitable model for population diversity studies. The objective of this study was to investigate the DRA gene diversity in three different populations of donkeys under infectious pressure of protozoan parasites, Theileria equi and Babesia caballi. Three populations of domestic donkeys from Italy (N = 68), Jordan (N = 43), and Kenya (N = 78) were studied.
dcterms:title
Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys
skos:prefLabel
Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys
skos:notation
RIV/62156489:43210/11:00181077!RIV14-MSM-43210___
n7:predkladatel
n8:orjk%3A43210
n5:aktivita
n17:S n17:P
n5:aktivity
P(GA523/09/1972), S
n5:cisloPeriodika
5
n5:dodaniDat
n11:2014
n5:domaciTvurceVysledku
n15:3671615 n15:8123462
n5:druhVysledku
n16:J
n5:duvernostUdaju
n13:S
n5:entitaPredkladatele
n6:predkladatel
n5:idSjednocenehoVysledku
200995
n5:idVysledku
RIV/62156489:43210/11:00181077
n5:jazykVysledku
n20:eng
n5:klicovaSlova
Theileria equi; Genetic diversity; Babesia caballi; Domestic donkey; Major histocompatibility class II DRA gene
n5:klicoveSlovo
n9:Theileria%20equi n9:Domestic%20donkey n9:Major%20histocompatibility%20class%20II%20DRA%20gene n9:Genetic%20diversity n9:Babesia%20caballi
n5:kodStatuVydavatele
NL - Nizozemsko
n5:kontrolniKodProRIV
[FCC43FD9A6D7]
n5:nazevZdroje
Infection, Genetics and Evolution
n5:obor
n10:EB
n5:pocetDomacichTvurcuVysledku
2
n5:pocetTvurcuVysledku
10
n5:projekt
n12:GA523%2F09%2F1972
n5:rokUplatneniVysledku
n11:2011
n5:svazekPeriodika
11
n5:tvurceVysledku
Qablan, Moneeb Putnová, Lenka Vrtková, Irena Vyskočil, Mirko Vránová, Marie Alloggio, Ingrid Hořín, Petr Sloboda, Michal Modrý, David Baumeisterova, Aneta
n5:wos
292256800043
s:issn
1567-1348
s:numberOfPages
6
n18:doi
10.1016/j.meegid.2011.04.010
n19:organizacniJednotka
43210