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Statements

Subject Item
n2:RIV%2F62156489%3A43210%2F11%3A00173752%21RIV12-AV0-43210___
rdf:type
n3:Vysledek skos:Concept
dcterms:description
Metallothioneins (MT) are a family of ubiquitous, biologically interesting proteins which have been isolated and studied in a wide variety of organisms, including prokaryotes, plants, invertebrates and vertebrates. Due to the property of MT being metal-inducible and, also, due to their high affinity to metal ions, homeostasis of heavy metal levels is probably their most important biological function. In addition, MT are involved in other important biochemical pathways including scavenging of reactive oxygen species, activation of transcription factors or participation in carcinogenesis. Detection and quantification of MT is not simple due to the high content of cysteine and relatively low molecular mass. These proteins can be detected very sensitively by electrochemical methods. Moreover, MT can be used as a part of biosensors. Metallothioneins (MT) are a family of ubiquitous, biologically interesting proteins which have been isolated and studied in a wide variety of organisms, including prokaryotes, plants, invertebrates and vertebrates. Due to the property of MT being metal-inducible and, also, due to their high affinity to metal ions, homeostasis of heavy metal levels is probably their most important biological function. In addition, MT are involved in other important biochemical pathways including scavenging of reactive oxygen species, activation of transcription factors or participation in carcinogenesis. Detection and quantification of MT is not simple due to the high content of cysteine and relatively low molecular mass. These proteins can be detected very sensitively by electrochemical methods. Moreover, MT can be used as a part of biosensors.
dcterms:title
Electrochemistry of metallothioneins Electrochemistry of metallothioneins
skos:prefLabel
Electrochemistry of metallothioneins Electrochemistry of metallothioneins
skos:notation
RIV/62156489:43210/11:00173752!RIV12-AV0-43210___
n3:predkladatel
n4:orjk%3A43210
n7:aktivita
n19:P
n7:aktivity
P(IAA401990701)
n7:dodaniDat
n22:2012
n7:domaciTvurceVysledku
n8:4995775 n8:3050106 n8:3790185 n8:7333323 n8:9100318 n8:8659443 n8:2307049
n7:druhVysledku
n10:D
n7:duvernostUdaju
n14:S
n7:entitaPredkladatele
n15:predkladatel
n7:idSjednocenehoVysledku
197051
n7:idVysledku
RIV/62156489:43210/11:00173752
n7:jazykVysledku
n20:eng
n7:klicovaSlova
protein; elektrochemistry; biological function
n7:klicoveSlovo
n13:protein n13:biological%20function n13:elektrochemistry
n7:kontrolniKodProRIV
[5665FCCF0893]
n7:mistoKonaniAkce
MENDELU
n7:mistoVydani
Brno
n7:nazevZdroje
XI. pracovní setkání fyzikálních chemiků a elektrochemiků
n7:obor
n17:CG
n7:pocetDomacichTvurcuVysledku
7
n7:pocetTvurcuVysledku
8
n7:projekt
n21:IAA401990701
n7:rokUplatneniVysledku
n22:2011
n7:tvurceVysledku
Kizek, René Šobrová, Pavlína Majzlík, Petr Trnková, Libuše Adam, Vojtěch Petrlová, Jitka Blaštík, Ondřej Fabrik, Ivo
n7:typAkce
n9:CST
n7:zahajeniAkce
2011-01-01+01:00
s:numberOfPages
5
n16:hasPublisher
Mendelova zemědělská a lesnická univerzita v Brně
n5:isbn
978-80-7375-514-0
n18:organizacniJednotka
43210