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Statements

Subject Item
n2:RIV%2F62156489%3A43210%2F10%3A00184598%21RIV12-AV0-43210___
rdf:type
n17:Vysledek skos:Concept
dcterms:description
Tumours of head and neck are one of the most incident tumour diseases. Well-timed diagnosis plays main role in their therapy. Aim of this work consisted in determination of metallothionein (MT), which could be new tumour marker. Determination of its concentration was carried out using electrochemical detection with use of differential pulse voltammetry. Concentrations of MT in samples of denaturized blood plasma of group of patients were about 2.3 uM with slight differences in accordance with localization of tumours. Contents of glutathione and total proteins in denaturized were determined chromatographically and by the help of Biuret reaction. Rate of concentrations levels of GSH/GSSG was varying from 1.31 to 17.66. Tumours of head and neck are one of the most incident tumour diseases. Well-timed diagnosis plays main role in their therapy. Aim of this work consisted in determination of metallothionein (MT), which could be new tumour marker. Determination of its concentration was carried out using electrochemical detection with use of differential pulse voltammetry. Concentrations of MT in samples of denaturized blood plasma of group of patients were about 2.3 uM with slight differences in accordance with localization of tumours. Contents of glutathione and total proteins in denaturized were determined chromatographically and by the help of Biuret reaction. Rate of concentrations levels of GSH/GSSG was varying from 1.31 to 17.66.
dcterms:title
Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area
skos:prefLabel
Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area
skos:notation
RIV/62156489:43210/10:00184598!RIV12-AV0-43210___
n3:aktivita
n18:P
n3:aktivity
P(GP301/09/P436), P(KAN208130801)
n3:cisloPeriodika
5
n3:dodaniDat
n4:2012
n3:domaciTvurceVysledku
n6:9100318 n6:8740658 n6:3931315 n6:9000240 n6:2307049 n6:4995775 n6:9584366
n3:druhVysledku
n8:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
253765
n3:idVysledku
RIV/62156489:43210/10:00184598
n3:jazykVysledku
n16:eng
n3:klicovaSlova
differential pulse voltammetry; tumor tissue; metallothionein
n3:klicoveSlovo
n13:metallothionein n13:differential%20pulse%20voltammetry n13:tumor%20tissue
n3:kodStatuVydavatele
IN - Indická republika
n3:kontrolniKodProRIV
[D48159298105]
n3:nazevZdroje
Journal of Biochemical Technology
n3:obor
n15:CB
n3:pocetDomacichTvurcuVysledku
7
n3:pocetTvurcuVysledku
8
n3:projekt
n5:KAN208130801 n5:GP301%2F09%2FP436
n3:rokUplatneniVysledku
n4:2010
n3:svazekPeriodika
2
n3:tvurceVysledku
Cernei, Natalia Vladimirovna Húska, Dalibor Majzlík, Petr Adam, Vojtěch Binková, Hana Masařík, Michal Kizek, René Zítka, Ondřej
s:issn
0974-2328
s:numberOfPages
2
n12:organizacniJednotka
43210