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Statements

Subject Item
n2:RIV%2F62156489%3A43210%2F08%3A00121294%21RIV09-AV0-43210___
rdf:type
skos:Concept n17:Vysledek
dcterms:description
A tumour disease or cancer, %22plague of the world%22, are words, which present a threat to humans as well as a subject of investigation for broaden scientific public. The success of treatment of the disease depends on many factors such as prevention, early and sensitive diagnostics. That means the sooner a cancer is detected, the better the chances to treat it successfully. In the last decade, several reports disclosed metallothioneins (MTs) expression as a useful prognostic factor for tumour progression and drug resistance in a variety of malignancies e.g. leukaemia, melanoma, breast, ovarian, renal, lung, pancreatic, gall bladder, esophageal, and basal cell carcinoma. The present work reports on investigation of involving of MTs in early detection of the disease as new tumour marker. A tumour disease or cancer, %22plague of the world%22, are words, which present a threat to humans as well as a subject of investigation for broaden scientific public. The success of treatment of the disease depends on many factors such as prevention, early and sensitive diagnostics. That means the sooner a cancer is detected, the better the chances to treat it successfully. In the last decade, several reports disclosed metallothioneins (MTs) expression as a useful prognostic factor for tumour progression and drug resistance in a variety of malignancies e.g. leukaemia, melanoma, breast, ovarian, renal, lung, pancreatic, gall bladder, esophageal, and basal cell carcinoma. The present work reports on investigation of involving of MTs in early detection of the disease as new tumour marker. Tumorové choroby jsou ve světe rozšíření a jejich léčba je intenzivně zkoumána. Úspěch léčby je závislí na mnoho faktorů jako je preventivní a citlivá diagnostika. V minulém desetiletí několik publikací dávalo expresi metalothioneinu do souvislosti s přítomností nádorového onemocnění jako je leukémie, nádor plic, vaječníků, pankreatu. V této práci uvádíme shrnutí výzkumu metalothioneinů v časné detekci a diagnostice tumorových markerů.
dcterms:title
Association of formation and progression of a tumour disease and level of metallothioneins Spojení tvorby a progrese nádorového onemocnění s úrovní metalothioneinu Association of formation and progression of a tumour disease and level of metallothioneins
skos:prefLabel
Association of formation and progression of a tumour disease and level of metallothioneins Spojení tvorby a progrese nádorového onemocnění s úrovní metalothioneinu Association of formation and progression of a tumour disease and level of metallothioneins
skos:notation
RIV/62156489:43210/08:00121294!RIV09-AV0-43210___
n3:aktivita
n19:P
n3:aktivity
P(IAA401990701)
n3:dodaniDat
n18:2009
n3:domaciTvurceVysledku
n6:2104237 n6:2307049 n6:8740658 n6:4995775
n3:druhVysledku
n4:D
n3:duvernostUdaju
n16:S
n3:entitaPredkladatele
n20:predkladatel
n3:idSjednocenehoVysledku
357168
n3:idVysledku
RIV/62156489:43210/08:00121294
n3:jazykVysledku
n8:eng
n3:klicovaSlova
metallothionein; tumour diseas
n3:klicoveSlovo
n13:tumour%20diseas n13:metallothionein
n3:kontrolniKodProRIV
[F80EC6C42B17]
n3:mistoVydani
Brno
n3:nazevZdroje
XII. pracovní setkání biochemiků a molekulárních biologů
n3:obor
n5:CE
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
12
n3:projekt
n11:IAA401990701
n3:rokUplatneniVysledku
n18:2008
n3:tvurceVysledku
Kizek, René Kukačka, Jiří Horaková, Zuzana Hraběta, Jan Křížková, Soňa Adam, Vojtěch Průša, Richard Sýkorová, E. Eckschlager, Tomáš Fabrik, Ivo Zítka, Ondřej Binková, Hana
s:numberOfPages
1
n14:hasPublisher
Masarykova univerzita
n12:isbn
978-80-210-4526-2
n10:organizacniJednotka
43210