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Statements

Subject Item
n2:RIV%2F62156489%3A43210%2F06%3A00095107%21RIV07-GA0-43210___
rdf:type
skos:Concept n18:Vysledek
dcterms:description
The object of the study was to determine if apoptosis of neutrophils and their subsequent elimination from the mammary gland by macrophages are modulated by an infection of Streptococcus uberis. After PBS and S. uberis administration the total number of both Annexin V+/PI- neutrophils and karyopycnotic neutrophils peaked at 24 hours. The highest percentages of Annexin V+/PI- neutrophils were detected at 72 hours after PBS and S. uberis, respectively. The highest percentages of karyopycnotic neutrophils were detected at 72 hours after PBS and 168 hours after S. uberis, respectively. The total number of MPO+ macrophages was the highest at 24 hour after PBS and 72 hours after S. uberis. The percentage of MPO+ macrophages was the highest at 72 hours after PBS and S. uberis. The results of this study demonstrate that during experimental infection of the mammary gland by S. uberis, the apoptosis of neutrophils is modulated. Předmětem bylo zjištění, zda apoptóza neutrofilů a jejich eliminace makrofágy jsou modulovány infekcí Streptococcus uberis. 24 h po intramammární aplikaci PBS a S. uberis došlo ke zvýšení počtu Annexin V+/PI- a karyopyknotických neutrofilů. Nejvyšší procentuální zastoupení těchto buněk bylo detekováno 72h po PBS a S. uberis. Nejvyšší procento karyopyknotických neutrofilů bylo detekováno 72h po PBS a 168 h po S. uberis. Celkový počet myeloperoxidáza pozitivních makrofágů byl nejvyšší 24 h po PBS a 72 h po S. uberis. Procentické zastoupení těchto buněk bylo nejvyšší 72 h po PBS a zároveň u S. uberis. Výsledky této studie demonstrují, že experimentální infekce mléčné žlázy skotu S. uberis moduluje apoptózu neutrofilních granulocytů. The object of the study was to determine if apoptosis of neutrophils and their subsequent elimination from the mammary gland by macrophages are modulated by an infection of Streptococcus uberis. After PBS and S. uberis administration the total number of both Annexin V+/PI- neutrophils and karyopycnotic neutrophils peaked at 24 hours. The highest percentages of Annexin V+/PI- neutrophils were detected at 72 hours after PBS and S. uberis, respectively. The highest percentages of karyopycnotic neutrophils were detected at 72 hours after PBS and 168 hours after S. uberis, respectively. The total number of MPO+ macrophages was the highest at 24 hour after PBS and 72 hours after S. uberis. The percentage of MPO+ macrophages was the highest at 72 hours after PBS and S. uberis. The results of this study demonstrate that during experimental infection of the mammary gland by S. uberis, the apoptosis of neutrophils is modulated.
dcterms:title
The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis Role apoptózy neutrofilních granulocytů během experimentální infekce mléčné žlázy Streptococcus uberis
skos:prefLabel
The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis Role apoptózy neutrofilních granulocytů během experimentální infekce mléčné žlázy Streptococcus uberis The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis
skos:notation
RIV/62156489:43210/06:00095107!RIV07-GA0-43210___
n3:strany
265;277
n3:aktivita
n10:P
n3:aktivity
P(GA524/03/1531)
n3:cisloPeriodika
51
n3:dodaniDat
n13:2007
n3:domaciTvurceVysledku
n14:3133265 n14:9869522
n3:druhVysledku
n6:J
n3:duvernostUdaju
n4:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
497890
n3:idVysledku
RIV/62156489:43210/06:00095107
n3:jazykVysledku
n12:eng
n3:klicovaSlova
apoptosis; neutrophils; streptococcus uberis
n3:klicoveSlovo
n11:apoptosis n11:neutrophils n11:streptococcus%20uberis
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[B67EE01A71DB]
n3:nazevZdroje
Veterinary Medicine Czech
n3:obor
n16:GJ
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
4
n3:projekt
n5:GA524%2F03%2F1531
n3:rokUplatneniVysledku
n13:2006
n3:tvurceVysledku
Sládek, Zbyšek Faldyna, Martin Ryšánek, Dušan Rýznarová, Helena
s:issn
0375-8427
s:numberOfPages
13
n15:organizacniJednotka
43210