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Statements

Subject Item

n2:RIV%2F62156489%3A43210%2F05%3A00086472%21RIV06-GA0-43210___

rdf:type

n18:Vysledek skos:Concept

dcterms:description

A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55_mol/l, ast 2.94_kat/l, alt 3.46_kat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace aas (varian). Plasma metallothionein levels were measured by electroanalytical technique--voltametric Brdicka reaction. In time of admission, the blood lead was 648_g/l, and metallothionein 153 _mol/l (normal values below 10_mol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the b-Pb decreased to 360 _g/l, u-Pb increased to 6019_g/24 h, p-metallothionein increased to 276_mol/l. After 5 days of chelation treatment, the b-Pb increased (535_g/l), p-metallothionen decreased (147_mol/l). The source of 6 months lead exposure was A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55_mol/l, ast 2.94_kat/l, alt 3.46_kat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace aas (varian). Plasma metallothionein levels were measured by electroanalytical technique--voltametric Brdicka reaction. In time of admission, the blood lead was 648_g/l, and metallothionein 153 _mol/l (normal values below 10_mol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the b-Pb decreased to 360 _g/l, u-Pb increased to 6019_g/24 h, p-metallothionein increased to 276_mol/l. After 5 days of chelation treatment, the b-Pb increased (535_g/l), p-metallothionen decreased (147_mol/l). The source of 6 months lead exposure was A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55_mol/l, ast 2.94_kat/l, alt 3.46_kat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace aas (varian). Plasma metallothionein levels were measured by electroanalytical technique--voltametric Brdicka reaction. In time of admission, the blood lead was 648_g/l, and metallothionein 153 _mol/l (normal values below 10_mol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the b-Pb decreased to 360 _g/l, u-Pb increased to 6019_g/24 h, p-metallothionein increased to 276_mol/l. After 5 days of chelation treatment, the b-Pb increased (535_g/l), p-metallothionen decreased (147_mol/l). The source of 6 months lead exposure was

dcterms:title

Hodnoty metalothioneinu v plazmě dítěte otráveného olovem Plasma metallothionein levels in lead poisoned child. Plasma metallothionein levels in lead poisoned child.

skos:prefLabel

Hodnoty metalothioneinu v plazmě dítěte otráveného olovem Plasma metallothionein levels in lead poisoned child. Plasma metallothionein levels in lead poisoned child.

skos:notation

RIV/62156489:43210/05:00086472!RIV06-GA0-43210___

n3:strany

S156;S157

n3:aktivita

n5:P

n3:aktivity

P(GP525/04/P132)

n3:cisloPeriodika

Suppl. 1

n3:dodaniDat

n10:2006

n3:domaciTvurceVysledku

n11:4995775 n11:3050106

n3:druhVysledku

n16:J

n3:duvernostUdaju

n9:S

n3:entitaPredkladatele

n6:predkladatel

n3:idSjednocenehoVysledku

536175

n3:idVysledku

RIV/62156489:43210/05:00086472

n3:jazykVysledku

n17:eng

n3:klicovaSlova

lead; metallothionein

n3:klicoveSlovo

n4:metallothionein n4:lead

n3:kodStatuVydavatele

NL - Nizozemsko

n3:kontrolniKodProRIV

[97E7F1547020]

n3:nazevZdroje

Toxicology Letters

n3:obor

n14:CG

n3:pocetDomacichTvurcuVysledku

2

n3:pocetTvurcuVysledku

5

n3:projekt

n13:GP525%2F04%2FP132

n3:rokUplatneniVysledku

n10:2005

n3:svazekPeriodika

158

n3:tvurceVysledku

Kízek, René Průša, Richard Kukacka, J. Blaštík, Ondřej Stuchlíková, Hana

s:issn

0378-4274

s:numberOfPages

2

n12:organizacniJednotka

43210