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Statements

Subject Item
n2:RIV%2F62156489%3A43210%2F05%3A00007606%21RIV06-GA0-43210___
rdf:type
n3:Vysledek skos:Concept
dcterms:description
A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55 mmol/l, AST 2.94 mkat/l, ALT 3.46 mkat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace AAS (Varian). Plasma metallothionein levels were measured by electroanalytical technique - voltametric Brdicka reaction. In time of admission, the blood lead was 648 mg/l, and metallothionein 153 mmol/l (normal values below 10 mmol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the B-Pb decreased to 360 mg/l, U-Pb increased to 6019 mg/24h, P-metallothionein increased to 276 mmol/l. After 5 days of chelation treatment, the B-Pb increased (535 mg/l), P-metallothionen decreased (147 mmol/l). The source of 6 months lead exposure wa A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55 mmol/l, AST 2.94 mkat/l, ALT 3.46 mkat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace AAS (Varian). Plasma metallothionein levels were measured by electroanalytical technique - voltametric Brdicka reaction. In time of admission, the blood lead was 648 mg/l, and metallothionein 153 mmol/l (normal values below 10 mmol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the B-Pb decreased to 360 mg/l, U-Pb increased to 6019 mg/24h, P-metallothionein increased to 276 mmol/l. After 5 days of chelation treatment, the B-Pb increased (535 mg/l), P-metallothionen decreased (147 mmol/l). The source of 6 months lead exposure wa A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55 mmol/l, AST 2.94 mkat/l, ALT 3.46 mkat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace AAS (Varian). Plasma metallothionein levels were measured by electroanalytical technique - voltametric Brdicka reaction. In time of admission, the blood lead was 648 mg/l, and metallothionein 153 mmol/l (normal values below 10 mmol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the B-Pb decreased to 360 mg/l, U-Pb increased to 6019 mg/24h, P-metallothionein increased to 276 mmol/l. After 5 days of chelation treatment, the B-Pb increased (535 mg/l), P-metallothionen decreased (147 mmol/l). The source of 6 months lead exposure wa
dcterms:title
Množství metalothioneinu u dítěte otráveného olovem Plasma metallothionein levels in lead poisoned child Plasma metallothionein levels in lead poisoned child
skos:prefLabel
Množství metalothioneinu u dítěte otráveného olovem Plasma metallothionein levels in lead poisoned child Plasma metallothionein levels in lead poisoned child
skos:notation
RIV/62156489:43210/05:00007606!RIV06-GA0-43210___
n6:strany
S156;S157
n6:aktivita
n11:P
n6:aktivity
P(GP525/04/P132)
n6:dodaniDat
n17:2006
n6:domaciTvurceVysledku
n12:4995775 n12:3050106 n12:2808374
n6:druhVysledku
n15:D
n6:duvernostUdaju
n19:S
n6:entitaPredkladatele
n18:predkladatel
n6:idSjednocenehoVysledku
536174
n6:idVysledku
RIV/62156489:43210/05:00007606
n6:jazykVysledku
n13:eng
n6:klicovaSlova
CPSA; lead; metallothionein
n6:klicoveSlovo
n14:CPSA n14:metallothionein n14:lead
n6:kontrolniKodProRIV
[C0EF71343565]
n6:nazevZdroje
Eurotox 2005; 42nd Congress of European Societes of Toxicology
n6:obor
n7:CG
n6:pocetDomacichTvurcuVysledku
3
n6:pocetTvurcuVysledku
5
n6:projekt
n16:GP525%2F04%2FP132
n6:rokUplatneniVysledku
n17:2005
n6:tvurceVysledku
Blaštík, Ondřej Kukacka, J. Stuchlíková, Hana Průša, Richard Kízek, René
s:issn
0378-4274
s:numberOfPages
2
n4:hasPublisher
Elsevier
n10:organizacniJednotka
43210