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Statements

Subject Item
n2:RIV%2F61989592%3A15310%2F12%3A33142328%21RIV13-MSM-15310___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
Aim. The aim of this study was to test an oral contrast solution with maghemite for the magnetic resonance imaging of small bowel diseases. Patients and methods. The study sample included 3 cohorts: 17 healthy volunteers (group A), 22 patients with small bowel disease (group C). Both groups underwent MR enterography and 24 patients with small bowel disease (group B) underwent magnetic resonance cholecystopancreaticography. Various concentrations in 1000 ml vs 500 ml of experimental solution were tested. All cohorts completed questionnaires evaluating the solution characteristics and side-efects during and after drinking. Results. A maghemite concentration of 800 mg /4 g bentonite in 1000 ml solution was sufficient for proper intraluminal lay-out. An experimental solution of 500 ml was sufficient for magnetic resonance cholecystopancreaticography and 1000 ml for MR enterography. There were no statistically significant differences between groups for taste, taste characteristic or appearance of the experimental solution. Side-effects experienced during drinking were: nausea (29.4%) and eructation (29.4%) in group A, in group B (42%) and diarrhoea (27.3%) in group C. Side-effects 2 h after drinking occured in group A (nausea 17.6%) and in group C (diarrhoea 47%). The best tolerance of experimental solution was found in group B with a higher median patient age than groups A and C. The experimental solution was evaluated more favorably in the older subjects (age over 50 years). Conclusion. The experimental oral solution with maghemite was well tolerated in all 3 groups. Our study supports its use in magnetic resonance practice. Aim. The aim of this study was to test an oral contrast solution with maghemite for the magnetic resonance imaging of small bowel diseases. Patients and methods. The study sample included 3 cohorts: 17 healthy volunteers (group A), 22 patients with small bowel disease (group C). Both groups underwent MR enterography and 24 patients with small bowel disease (group B) underwent magnetic resonance cholecystopancreaticography. Various concentrations in 1000 ml vs 500 ml of experimental solution were tested. All cohorts completed questionnaires evaluating the solution characteristics and side-efects during and after drinking. Results. A maghemite concentration of 800 mg /4 g bentonite in 1000 ml solution was sufficient for proper intraluminal lay-out. An experimental solution of 500 ml was sufficient for magnetic resonance cholecystopancreaticography and 1000 ml for MR enterography. There were no statistically significant differences between groups for taste, taste characteristic or appearance of the experimental solution. Side-effects experienced during drinking were: nausea (29.4%) and eructation (29.4%) in group A, in group B (42%) and diarrhoea (27.3%) in group C. Side-effects 2 h after drinking occured in group A (nausea 17.6%) and in group C (diarrhoea 47%). The best tolerance of experimental solution was found in group B with a higher median patient age than groups A and C. The experimental solution was evaluated more favorably in the older subjects (age over 50 years). Conclusion. The experimental oral solution with maghemite was well tolerated in all 3 groups. Our study supports its use in magnetic resonance practice.
dcterms:title
MR enterography with a new negative oral contrast solution containing maghemite nanoparticles MR enterography with a new negative oral contrast solution containing maghemite nanoparticles
skos:prefLabel
MR enterography with a new negative oral contrast solution containing maghemite nanoparticles MR enterography with a new negative oral contrast solution containing maghemite nanoparticles
skos:notation
RIV/61989592:15310/12:33142328!RIV13-MSM-15310___
n11:predkladatel
n17:orjk%3A15310
n3:aktivita
n16:I
n3:aktivity
I
n3:cisloPeriodika
3
n3:dodaniDat
n5:2013
n3:domaciTvurceVysledku
n15:2612526 n15:8570647 n15:7321023 n15:9251189
n3:druhVysledku
n18:J
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n19:predkladatel
n3:idSjednocenehoVysledku
152254
n3:idVysledku
RIV/61989592:15310/12:33142328
n3:jazykVysledku
n7:eng
n3:klicovaSlova
MRCP; maghemite; MR enterography
n3:klicoveSlovo
n13:MR%20enterography n13:MRCP n13:maghemite
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[D694D2AE513B]
n3:nazevZdroje
Biomedical Papers-Olomouc
n3:obor
n4:FP
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
7
n3:rokUplatneniVysledku
n5:2012
n3:svazekPeriodika
156
n3:tvurceVysledku
Zbořil, Radek Marková, Ingrid Tuček, Jiří Poláková, Kateřina Mašláň, Miroslav Novák, Pavel Heřman, Miroslav
s:issn
1213-8118
s:numberOfPages
7
n14:doi
10.5507/bp.2012.001
n10:organizacniJednotka
15310