This HTML5 document contains 56 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n16http://linked.opendata.cz/ontology/domain/vavai/riv/statVydaniPatentuVzoru/
dctermshttp://purl.org/dc/terms/
n19http://localhost/temp/predkladatel/
n15http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n13http://linked.opendata.cz/resource/domain/vavai/projekt/
n11http://linked.opendata.cz/ontology/domain/vavai/riv/uzemniOchranaPatentu/
n21http://linked.opendata.cz/ontology/domain/vavai/
n14http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F61989592%3A15310%2F10%3A10212652%21RIV11-GA0-15310___/
n22http://linked.opendata.cz/resource/domain/vavai/zamer/
skoshttp://www.w3.org/2004/02/skos/core#
n18http://linked.opendata.cz/ontology/domain/vavai/riv/vyuzitiPatentuVzoru/
n4http://linked.opendata.cz/ontology/domain/vavai/riv/
n10http://linked.opendata.cz/ontology/domain/vavai/riv/licencniPoplatek/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n20http://linked.opendata.cz/ontology/domain/vavai/riv/vyuzitiJinymSubjektem/
n5http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n23http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n12http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n7http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n17http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n8http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F61989592%3A15310%2F10%3A10212652%21RIV11-GA0-15310___
rdf:type
skos:Concept n21:Vysledek
dcterms:description
The invention relates to 3-,5-,7-trisubstituted pyrazolo(4,3-d)pyrimidines represented by the general formula (I), and substituted alkyl, cycloalkyl, cycloheteroalkyl, cycloalkyl, alkyl, aryl or alkylaryl group, R5 is halogen, -NHNH2, -NHOH, NHCONH2, guanylo (NH-C(NH)NH2) an optionally substituted C1-C6 alkyl, alkenyl, alkinyl, C3-C15 cycloalkyl, Rf (C3-C15 cycloalkyl), heterocycle, heteroalkyl, aryl, heteroaryl, arylalkyl, cycloheteroalkyl, cycloheteroalkyl alkyl, heteroarylalkyl group etc.This invention relates to new pyrazolo(4,3-d)pyrimidine derivatives and to their use in suitable utilities, especially diagnostic and therapeutic methods. More specifically, the present invention also relates to the use of 3,5,7-trisubstituted pyrazolo(4,3-d)pyrimidines or a pharmaceutically acceptable salt thereof in combination with cytostatics in the preparation of a medicament for treating cancer. The invention relates to 3-,5-,7-trisubstituted pyrazolo(4,3-d)pyrimidines represented by the general formula (I), and substituted alkyl, cycloalkyl, cycloheteroalkyl, cycloalkyl, alkyl, aryl or alkylaryl group, R5 is halogen, -NHNH2, -NHOH, NHCONH2, guanylo (NH-C(NH)NH2) an optionally substituted C1-C6 alkyl, alkenyl, alkinyl, C3-C15 cycloalkyl, Rf (C3-C15 cycloalkyl), heterocycle, heteroalkyl, aryl, heteroaryl, arylalkyl, cycloheteroalkyl, cycloheteroalkyl alkyl, heteroarylalkyl group etc.This invention relates to new pyrazolo(4,3-d)pyrimidine derivatives and to their use in suitable utilities, especially diagnostic and therapeutic methods. More specifically, the present invention also relates to the use of 3,5,7-trisubstituted pyrazolo(4,3-d)pyrimidines or a pharmaceutically acceptable salt thereof in combination with cytostatics in the preparation of a medicament for treating cancer.
dcterms:title
Novel pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy Novel pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy
skos:prefLabel
Novel pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy Novel pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy
skos:notation
RIV/61989592:15310/10:10212652!RIV11-GA0-15310___
n4:aktivita
n7:Z n7:P
n4:aktivity
P(GA301/08/1649), P(GA522/09/1576), Z(AV0Z5038910)
n4:cisloPatentuVzoru
CA2480409
n4:datumUdeleniPatentuVzoru
2010-06-22+02:00
n4:dodaniDat
n8:2011
n4:domaciTvurceVysledku
n15:9130241 n15:4712048 n15:9896821 n15:9961216
n4:druhVysledku
n9:P
n4:duvernostUdaju
n23:S
n4:entitaPredkladatele
n14:predkladatel
n4:idSjednocenehoVysledku
275450
n4:idVysledku
RIV/61989592:15310/10:10212652
n4:jazykVysledku
n12:eng
n4:klicovaSlova
novel, pyrazolo[4,3-D]pyrimidines, process, preparation, method, therapy
n4:klicoveSlovo
n5:3-D%5Dpyrimidines n5:preparation n5:method n5:novel n5:pyrazolo%5B4 n5:process n5:therapy
n4:kontrolniKodProRIV
[E4138C0AA5E8]
n4:licencniPoplatek
n10:A
n4:mistoVydaniPatentuVzoru
Gatineau
n4:nazevVydavatelePatentuVzoru
Canadian Intellectual Property Office (CIPO) Industry Canada
n4:obor
n17:CC
n4:pocetDomacichTvurcuVysledku
4
n4:pocetTvurcuVysledku
5
n4:projekt
n13:GA301%2F08%2F1649 n13:GA522%2F09%2F1576
n4:rokUplatneniVysledku
n8:2010
n4:statVydaniPatentuVzoru
n16:CA
n4:tvurceVysledku
Moravcová, Daniela Lenobel, René HAVLÍČEK, Libor Kryštof, Vladimír Strnad, Miroslav
n4:uzemniOchranaPatentu
n11:D
n4:vlastnik
n14:vlastnikVysledku
n4:vyuzitiJinymSubjektem
n20:A
n4:vyuzitiPatentuVzoru
n18:B
n4:zamer
n22:AV0Z5038910
n4:vlastnikPatentuVzoru
Univerzita Palackého v Olomouci a Ústav Experimentální Botaniky AV ČR v Praze
n19:organizacniJednotka
15310