This HTML5 document contains 50 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n12http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F61989592%3A15310%2F10%3A10212120%21RIV11-MSM-15310___/
n3http://localhost/temp/predkladatel/
n13http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n8http://linked.opendata.cz/resource/domain/vavai/projekt/
n15http://linked.opendata.cz/ontology/domain/vavai/
n14http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n4http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n10http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n16http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n18http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n7http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n19http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n5http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n11http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F61989592%3A15310%2F10%3A10212120%21RIV11-MSM-15310___
rdf:type
skos:Concept n15:Vysledek
dcterms:description
This paper reports an easy and highly reproducible preparation route, using self-emulsifying technology, for an orally administered high quality magnetically responsive drug delivery system. Hydrophobic iron oxide nanoparticles of about 5 nm in diameter were prepared and incorporated into the lipid core of the produced oil droplets of a self-nanoemulsifying drug delivery system (MagC(18)/SNEDDS). The produced nanoemulsion exhibits colloidal stability at high ionic strengths and temperatures. The observed value of the saturation magnetization at 2 K is approximate to 4.1 emu g(-1). The nanoemulsion displayed the magnetic properties of a non-interacting assembly of superparamagnetic particles and a low blocking temperature. Moreover the effect of MagC(18)/SNEDDS on biological systems in vitro was investigated in rodent fibroblasts (3T3 cells). The cytotoxicity studies show that none of the formulations tested affected cell activity significantly over the 24 h incubation. This paper reports an easy and highly reproducible preparation route, using self-emulsifying technology, for an orally administered high quality magnetically responsive drug delivery system. Hydrophobic iron oxide nanoparticles of about 5 nm in diameter were prepared and incorporated into the lipid core of the produced oil droplets of a self-nanoemulsifying drug delivery system (MagC(18)/SNEDDS). The produced nanoemulsion exhibits colloidal stability at high ionic strengths and temperatures. The observed value of the saturation magnetization at 2 K is approximate to 4.1 emu g(-1). The nanoemulsion displayed the magnetic properties of a non-interacting assembly of superparamagnetic particles and a low blocking temperature. Moreover the effect of MagC(18)/SNEDDS on biological systems in vitro was investigated in rodent fibroblasts (3T3 cells). The cytotoxicity studies show that none of the formulations tested affected cell activity significantly over the 24 h incubation.
dcterms:title
The preparation of magnetically guided lipid based nanoemulsions using self-emulsifying technology The preparation of magnetically guided lipid based nanoemulsions using self-emulsifying technology
skos:prefLabel
The preparation of magnetically guided lipid based nanoemulsions using self-emulsifying technology The preparation of magnetically guided lipid based nanoemulsions using self-emulsifying technology
skos:notation
RIV/61989592:15310/10:10212120!RIV11-MSM-15310___
n4:aktivita
n7:P n7:Z
n4:aktivity
P(KAN115600801), P(KAN200380801), Z(MSM6198959218)
n4:cisloPeriodika
5
n4:dodaniDat
n11:2011
n4:domaciTvurceVysledku
n13:9251189
n4:druhVysledku
n5:J
n4:duvernostUdaju
n16:S
n4:entitaPredkladatele
n12:predkladatel
n4:idSjednocenehoVysledku
281370
n4:idVysledku
RIV/61989592:15310/10:10212120
n4:jazykVysledku
n18:eng
n4:klicovaSlova
particles; formulations; oxide nanoparticles; oral delivery; drug-delivery systems
n4:klicoveSlovo
n10:formulations n10:oxide%20nanoparticles n10:drug-delivery%20systems n10:particles n10:oral%20delivery
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[F27C47F2E0D0]
n4:nazevZdroje
Nanotechnology
n4:obor
n19:CF
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
8
n4:projekt
n8:KAN200380801 n8:KAN115600801
n4:rokUplatneniVysledku
n11:2010
n4:svazekPeriodika
21
n4:tvurceVysledku
Bouropoulos, Nikolaos Bakandritsos, Aristides Parker, Terry L. Mullertz, Anette Fatouros, Dimitros G. Kallinteri, Paraskevi Favretto, Marco E. Zbořil, Radek
n4:wos
000273348400004
n4:zamer
n14:MSM6198959218
s:issn
0957-4484
s:numberOfPages
8
n3:organizacniJednotka
15310