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Statements

Subject Item
n2:RIV%2F61989592%3A15310%2F05%3A10223264%21RIV12-MSM-15310___
rdf:type
skos:Concept n20:Vysledek
dcterms:description
The present invention relates to the use of a compound of formula (I), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, in the preparation of a medicament for treating a patient suffering from leukaemia, cancer or other proliferative disorder. A further embodiment relates to the use a compound of formula (I) in an assay for detecting the phosphorylation state of cellular substrates. The present invention also relates to novel compounds of formula (I), and the chemical synthesis thereof. The present invention relates to the use of a compound of formula (I), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, in the preparation of a medicament for treating a patient suffering from leukaemia, cancer or other proliferative disorder. A further embodiment relates to the use a compound of formula (I) in an assay for detecting the phosphorylation state of cellular substrates. The present invention also relates to novel compounds of formula (I), and the chemical synthesis thereof.
dcterms:title
Triterpenoid derivatives and their use as antiproliferative agents Triterpenoid derivatives and their use as antiproliferative agents
skos:prefLabel
Triterpenoid derivatives and their use as antiproliferative agents Triterpenoid derivatives and their use as antiproliferative agents
skos:notation
RIV/61989592:15310/05:10223264!RIV12-MSM-15310___
n3:aktivita
n14:Z
n3:aktivity
Z(MSM6198959216)
n3:cisloPatentuVzoru
EP1289977
n3:datumUdeleniPatentuVzoru
2005-03-23+01:00
n3:dodaniDat
n5:2012
n3:domaciTvurceVysledku
n15:8434573
n3:druhVysledku
n11:P
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
547334
n3:idVysledku
RIV/61989592:15310/05:10223264
n3:jazykVysledku
n18:eng
n3:klicovaSlova
modification; lupane; derivatives; cytotoxic; antitumour activity; betulinic acid; betulin
n3:klicoveSlovo
n4:derivatives n4:lupane n4:cytotoxic n4:betulin n4:antitumour%20activity n4:modification n4:betulinic%20acid
n3:kontrolniKodProRIV
[FA1C7D33341C]
n3:licencniPoplatek
n19:A
n3:mistoVydaniPatentuVzoru
Munich, The Hague, Berlin, Vienna, Brussels
n3:nazevVydavatelePatentuVzoru
Evropský patentový úřad
n3:obor
n21:CC
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
2
n3:rokUplatneniVysledku
n5:2005
n3:tvurceVysledku
Hajdúch, Marián Šarek, Jan
n3:uzemniOchranaPatentu
n12:A
n3:vlastnik
n16:vlastnikVysledku
n3:vyuzitiJinymSubjektem
n10:A
n3:vyuzitiPatentuVzoru
n8:B
n3:zamer
n13:MSM6198959216
n3:vlastnikPatentuVzoru
Univerzita Palackého v Olomouci; Univerzita Karlova v Praze;
n9:organizacniJednotka
15310